Cargando…

Enhanced Intestinal Permeability of Cefixime by Self-Emulsifying Drug Delivery System: In-Vitro and Ex-Vivo Characterization

Background: Cefixime (CFX) belongs to a group of third-generation cephalosporin antibiotics with low water solubility and low intestinal permeability, which ultimately leads to significantly low bioavailability. Aim: This study aimed to increase solubility, improve drug release, and intestinal perme...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mahmood, Arshad, Khan, Laraib, Ijaz, Muhammad, Nazir, Imran, Naseem, Mahrukh, Tahir, Muhammad Azam, Aamir, Muhammad Naeem, Rehman, Masood Ur, Asim, Mulazim Hussain
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055996/ https://www.ncbi.nlm.nih.gov/pubmed/36985803 http://dx.doi.org/10.3390/molecules28062827

Ejemplares similares

Nano-Formulation Based Intravesical Drug Delivery Systems: An Overview of Versatile Approaches to Improve Urinary Bladder Diseases
por: Sarfraz, Muhammad, et al.
Publicado: (2022)

Development and in vitro Evaluation of Gastro-protective Aceclofenac-loaded Self-emulsifying Drug Delivery System
por: Jianxian, Chen, et al.
Publicado: (2020)

Photocatalytic Degradation of Cefixime Trihydrate by Bismuth Ferrite Nanoparticles
por: Nazir, Ammara, et al.
Publicado: (2021)

Artemisia brevifolia Wall. Ex DC Enhances Cefixime Susceptibility by Reforming Antimicrobial Resistance
por: Zafar, Aroosa, et al.
Publicado: (2023)

Development of mucus-penetrating iodine loaded self-emulsifying system for local vaginal delivery
por: Fida, Saima, et al.
Publicado: (2022)

Self-Emulsifying Drug Delivery Systems (SEDDS): Measuring Energy Dynamics to Determine Thermodynamic and Kinetic Stability
por: Rehman, Fiza Ur, et al.
Publicado: (2022)

Changes in Intestinal Permeability Ex Vivo and Immune Cell Activation by Three Commonly Used Emulsifiers
por: Oscarsson, Elin, et al.
Publicado: (2020)

Use of diesel and emulsified diesel in CI engine: A comparative analysis of engine characteristics
por: Hassan, Zain Ul, et al.
Publicado: (2021)

Per-6-Thiolated Cyclodextrins: A Novel Type of Permeation Enhancing Excipients for BCS Class IV Drugs
por: Asim, Mulazim Hussain, et al.
Publicado: (2020)

Self-emulsifying drug delivery systems: A versatile approach to enhance the oral delivery of BCS class III drug via hydrophobic ion pairing
por: Asad, Muhammad, et al.
Publicado: (2023)

Non-ionic thiolated cyclodextrins – the next generation
por: Moghadam, Ali, et al.
Publicado: (2018)

Cefixime and cefixime-clavulanate for screening and confirmation of extended-spectrum beta-lactamases in Escherichia coli
por: Al-Tamimi, Mohammad, et al.
Publicado: (2022)

Formulation Development and Ex-Vivo Permeability of Curcumin Hydrogels under the Influence of Natural Chemical Enhancers
por: Nawaz, Asif, et al.
Publicado: (2022)

Anti-Proliferative and Apoptosis-Inducing Activity of Acacia Modesta and Opuntia Monocantha Extracts on HeLa Cells
por: Abid, Farah, et al.
Publicado: (2020)

Threat to Cefixime Treatment for Gonorrhea
por: Yokoi, Shigeaki, et al.
Publicado: (2007)

Ex Vivo Expansion of Functional Human UCB-HSCs/HPCs by Coculture with AFT024-hkirre Cells
por: Khan, Muti ur Rehman, et al.
Publicado: (2014)

Self-Emulsifying Drug Delivery Systems: Hydrophobic Drug Polymer Complexes Provide a Sustained Release in Vitro
por: Malkawi, Ahmad, et al.
Publicado: (2020)

Voriconazole Cyclodextrin Based Polymeric Nanobeads for Enhanced Solubility and Activity: In Vitro/In Vivo and Molecular Simulation Approach
por: Farooq, Mudassir, et al.
Publicado: (2023)

Development and In Vitro/Ex Vivo Evaluation of Lecithin-Based Deformable Transfersomes and Transfersome-Based Gels for Combined Dermal Delivery of Meloxicam and Dexamethasone
por: Khan, Muhammad Imran, et al.
Publicado: (2022)

Cefixime: Anaphylactic shock: case report
Publicado: (2020)

Effect of Layer-by-Layer (LbL) Encapsulation of Nano-Emulsified Fish Oil on Their Digestibility Ex Vivo and Skin Permeability In Vitro
por: Jung, Eun Young, et al.
Publicado: (2016)

Enhanced Oral Bioavailability of Epalrestat SBE(7)-β-CD Complex Loaded Chitosan Nanoparticles: Preparation, Characterization and in-vivo Pharmacokinetic Evaluation
por: Alvi, Zunaira, et al.
Publicado: (2021)

3,4-Dimethylpyrano[2,3-c]pyrazol-6(2H)-one
por: Shahid, Bilal, et al.
Publicado: (2012)

Troxerutin flavonoid has neuroprotective properties and increases neurite outgrowth and migration of neural stem cells from the subventricular zone
por: Masood, Muhammad Irfan, et al.
Publicado: (2020)

Comparative study of heat and mass transfer of generalized MHD Oldroyd-B bio-nano fluid in a permeable medium with ramped conditions
por: Wang, Fuzhang, et al.
Publicado: (2021)

Effect of Quinolones Versus Cefixime on International Normalized Ratio Levels After Valve Replacement Surgery with Warfarin Therapy
por: Liaqat, Anam, et al.
Publicado: (2019)

Neisseria gonorrhoeae Resistant to Ceftriaxone and Cefixime, Argentina
por: Gianecini, Ricardo, et al.
Publicado: (2016)

Clinical Efficacy of Cefixime for the Treatment of Early Syphilis
por: Stafylis, Chrysovalantis, et al.
Publicado: (2021)

Fabrication, in vitro and ex vivo evaluation of proliposomes and liposomal derived gel for enhanced solubility and permeability of diacerein
por: Shah, Hassan, et al.
Publicado: (2021)

Using the genetic characteristics of Neisseria gonorrhoeae strains with decreased susceptibility to cefixime to develop a molecular assay to predict cefixime susceptibility
por: Deng, Xiaomeng, et al.
Publicado: (2019)

Construction of optical solitons of magneto-optic waveguides with anti-cubic law nonlinearity
por: Asjad, Muhammad Imran, et al.
Publicado: (2021)

Development and Evaluation of a Physiologically Based Pharmacokinetic Drug-Disease Model of Propranolol for Suggesting Model Informed Dosing in Liver Cirrhosis Patients
por: Kalam, Muhammad Nasir, et al.
Publicado: (2021)

Spectrum of Clinical Presentation of Celiac Disease in Pediatric Population
por: ., Imran, et al.
Publicado: (2021)

A study to evaluate the impact of COVID-19 on Lifestyle of Medical students
por: Tahir, Sania Mumtaz, et al.
Publicado: (2022)

Leveraging the Role of Dynamic Reconfigurable Antennas in Viewpoint of Industry 4.0 and Beyond
por: Jabbar, Abdul, et al.
Publicado: (2023)

(2E)-3-(2-Chloro-6-methyl-3-quinolyl)-1-(1-naphthyl)prop-2-en-1-one
por: Rizvi, Syed Umar Farooq, et al.
Publicado: (2010)

Corticosterone Methyl Oxidase Type 1 (CMO1) Deficiency Due to CYP11B2 Mutation: Two Case Reports
por: Ur Rehman, Saad, et al.
Publicado: (2023)

Predatory functional response and fitness parameters of Orius strigicollis Poppius when fed Bemisia tabaci and Trialeurodes vaporariorum as determined by age-stage, two-sex life table
por: Rehman, Shakeel Ur, et al.
Publicado: (2020)

Spectrofluorimetric determination of cefixime using terbium-danofloxacin probe
por: Manzoori, Jamshid L., et al.
Publicado: (2014)

Cefixime: Thrombocytopenia, oral erosions and petechiae: case report
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_aqoj6nu0foqh6tsemnulrkm4ln