Metformin Suppresses Thioacetamide-Induced Chronic Kidney Disease in Association with the Upregulation of AMPK and Downregulation of Oxidative Stress and Inflammation as Well as Dyslipidemia and Hypertension

Toxic chemicals such as carbon tetrachloride and thioacetamide (TAA) are reported to induce hepato-nephrotoxicity. The potential protective outcome of the antidiabetic and pleiotropic drug metformin against TAA-induced chronic kidney disease in association with the modulation of AMP-activated protei...

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Detalles Bibliográficos
Autores principales: Alshahrani, Mohammad Y., Ebrahim, Hasnaa A., Alqahtani, Saeed M., Bayoumy, Nervana M., Kamar, Samaa S., ShamsEldeen, Asmaa M., Haidara, Mohamed A., Al-Ani, Bahjat, Albawardi, Alia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056045/
https://www.ncbi.nlm.nih.gov/pubmed/36985728
http://dx.doi.org/10.3390/molecules28062756

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