Past, Present, and a Glance into the Future of Multiple Myeloma Treatment

Multiple myeloma (MM) is a challenging hematological cancer which typically grows in bone marrow. MM accounts for 10% of hematological malignancies and 1.8% of cancers. The recent treatment strategies have significantly improved progression-free survival for MM patients in the last decade; however,...

Descripción completa

Detalles Bibliográficos
Autores principales: Elbezanti, Weam Othman, Challagundla, Kishore B., Jonnalagadda, Subash C., Budak-Alpdogan, Tulin, Pandey, Manoj K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056051/
https://www.ncbi.nlm.nih.gov/pubmed/36986514
http://dx.doi.org/10.3390/ph16030415
Descripción
Sumario:Multiple myeloma (MM) is a challenging hematological cancer which typically grows in bone marrow. MM accounts for 10% of hematological malignancies and 1.8% of cancers. The recent treatment strategies have significantly improved progression-free survival for MM patients in the last decade; however, a relapse for most MM patients is inevitable. In this review we discuss current treatment, important pathways for proliferation, survival, immune suppression, and resistance that could be targeted for future treatments.

Ejemplares similares