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Exploring Iberian Peninsula Lamiaceae as Potential Therapeutic Approaches in Wound Healing

Skin tissue has a crucial role in protecting the human body from external harmful agents, preventing wounds that frequently demand proper healing approaches. The ethnobotanical knowledge of specific regions with further investigation on their medicinal plants has been paramount to create new and eff...

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Autores principales: Marques, Mário P., Mendonça, Laura, Neves, Beatriz G., Varela, Carla, Oliveira, Paulo, Cabral, Célia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056130/
https://www.ncbi.nlm.nih.gov/pubmed/36986446
http://dx.doi.org/10.3390/ph16030347
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author Marques, Mário P.
Mendonça, Laura
Neves, Beatriz G.
Varela, Carla
Oliveira, Paulo
Cabral, Célia
author_facet Marques, Mário P.
Mendonça, Laura
Neves, Beatriz G.
Varela, Carla
Oliveira, Paulo
Cabral, Célia
author_sort Marques, Mário P.
collection PubMed
description Skin tissue has a crucial role in protecting the human body from external harmful agents, preventing wounds that frequently demand proper healing approaches. The ethnobotanical knowledge of specific regions with further investigation on their medicinal plants has been paramount to create new and effective therapeutical agents, including for dermatological purposes. This review attempts, for the first time, to investigate the traditional applications of Lamiaceae medicinal plants that are already used by local communities in the Iberian Peninsula in wound healing. Henceforward, Iberian ethnobotanical surveys were reviewed, and the information about the traditional wound healing practices of Lamiaceae was comprehensively summarized. Afterwards, the scientific validation of each Lamiaceae species was exhaustively checked. From this, eight out of twenty-nine Lamiaceae medicinal plants were highlighted by their wound-related pharmacological evidence and are in-depth presented in this review. We suggest that future studies should focus on the isolation and identification of the active molecules of these Lamiaceae, followed by robust clinical trials that may confirm the security and effectiveness of such natural-based approaches. This will in turn pave the way for more reliable wound healing treatments.
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spelling pubmed-100561302023-03-30 Exploring Iberian Peninsula Lamiaceae as Potential Therapeutic Approaches in Wound Healing Marques, Mário P. Mendonça, Laura Neves, Beatriz G. Varela, Carla Oliveira, Paulo Cabral, Célia Pharmaceuticals (Basel) Review Skin tissue has a crucial role in protecting the human body from external harmful agents, preventing wounds that frequently demand proper healing approaches. The ethnobotanical knowledge of specific regions with further investigation on their medicinal plants has been paramount to create new and effective therapeutical agents, including for dermatological purposes. This review attempts, for the first time, to investigate the traditional applications of Lamiaceae medicinal plants that are already used by local communities in the Iberian Peninsula in wound healing. Henceforward, Iberian ethnobotanical surveys were reviewed, and the information about the traditional wound healing practices of Lamiaceae was comprehensively summarized. Afterwards, the scientific validation of each Lamiaceae species was exhaustively checked. From this, eight out of twenty-nine Lamiaceae medicinal plants were highlighted by their wound-related pharmacological evidence and are in-depth presented in this review. We suggest that future studies should focus on the isolation and identification of the active molecules of these Lamiaceae, followed by robust clinical trials that may confirm the security and effectiveness of such natural-based approaches. This will in turn pave the way for more reliable wound healing treatments. MDPI 2023-02-24 /pmc/articles/PMC10056130/ /pubmed/36986446 http://dx.doi.org/10.3390/ph16030347 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Marques, Mário P.
Mendonça, Laura
Neves, Beatriz G.
Varela, Carla
Oliveira, Paulo
Cabral, Célia
Exploring Iberian Peninsula Lamiaceae as Potential Therapeutic Approaches in Wound Healing
title Exploring Iberian Peninsula Lamiaceae as Potential Therapeutic Approaches in Wound Healing
title_full Exploring Iberian Peninsula Lamiaceae as Potential Therapeutic Approaches in Wound Healing
title_fullStr Exploring Iberian Peninsula Lamiaceae as Potential Therapeutic Approaches in Wound Healing
title_full_unstemmed Exploring Iberian Peninsula Lamiaceae as Potential Therapeutic Approaches in Wound Healing
title_short Exploring Iberian Peninsula Lamiaceae as Potential Therapeutic Approaches in Wound Healing
title_sort exploring iberian peninsula lamiaceae as potential therapeutic approaches in wound healing
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056130/
https://www.ncbi.nlm.nih.gov/pubmed/36986446
http://dx.doi.org/10.3390/ph16030347
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