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Simulation of Foot-and-Mouth Disease Spread and Effects of Mitigation Strategies to Support Veterinary Contingency Planning in Denmark

To forge a path towards livestock disease emergency preparedness in Denmark, 15 different strategies to mitigate foot-and-mouth disease (FMD) were examined by modelling epidemics initiated in cattle, pig or small ruminant herds across various production systems located in four different Danish regio...

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Autores principales: Conrady, Beate, Mortensen, Sten, Nielsen, Søren Saxmose, Houe, Hans, Calvo-Artavia, Francisco Fernando, Ellis-Iversen, Johanne, Boklund, Anette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056164/
https://www.ncbi.nlm.nih.gov/pubmed/36986357
http://dx.doi.org/10.3390/pathogens12030435
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author Conrady, Beate
Mortensen, Sten
Nielsen, Søren Saxmose
Houe, Hans
Calvo-Artavia, Francisco Fernando
Ellis-Iversen, Johanne
Boklund, Anette
author_facet Conrady, Beate
Mortensen, Sten
Nielsen, Søren Saxmose
Houe, Hans
Calvo-Artavia, Francisco Fernando
Ellis-Iversen, Johanne
Boklund, Anette
author_sort Conrady, Beate
collection PubMed
description To forge a path towards livestock disease emergency preparedness in Denmark, 15 different strategies to mitigate foot-and-mouth disease (FMD) were examined by modelling epidemics initiated in cattle, pig or small ruminant herds across various production systems located in four different Danish regions (Scenario 1), or in one specific livestock production system within each of the three species geographically distributed throughout Denmark (Scenario 2). When additional mitigation strategies were implemented on top of basic control strategies in the European foot-and-mouth disease spread model (EuFMDiS), no significant benefits were predicted in terms of the number of infected farms, the epidemic control duration, and the total economic cost. Further, the model results indicated that the choice of index herd, the resources for outbreak control, and the detection time of FMD significantly influenced the course of an epidemic. The present study results emphasise the importance of basic mitigation strategies, including an effective back-and-forward traceability system, adequate resources for outbreak response, and a high level of awareness among farmers and veterinarians concerning the detection and reporting of FMD at an early stage of an outbreak for FMD control in Denmark.
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spelling pubmed-100561642023-03-30 Simulation of Foot-and-Mouth Disease Spread and Effects of Mitigation Strategies to Support Veterinary Contingency Planning in Denmark Conrady, Beate Mortensen, Sten Nielsen, Søren Saxmose Houe, Hans Calvo-Artavia, Francisco Fernando Ellis-Iversen, Johanne Boklund, Anette Pathogens Article To forge a path towards livestock disease emergency preparedness in Denmark, 15 different strategies to mitigate foot-and-mouth disease (FMD) were examined by modelling epidemics initiated in cattle, pig or small ruminant herds across various production systems located in four different Danish regions (Scenario 1), or in one specific livestock production system within each of the three species geographically distributed throughout Denmark (Scenario 2). When additional mitigation strategies were implemented on top of basic control strategies in the European foot-and-mouth disease spread model (EuFMDiS), no significant benefits were predicted in terms of the number of infected farms, the epidemic control duration, and the total economic cost. Further, the model results indicated that the choice of index herd, the resources for outbreak control, and the detection time of FMD significantly influenced the course of an epidemic. The present study results emphasise the importance of basic mitigation strategies, including an effective back-and-forward traceability system, adequate resources for outbreak response, and a high level of awareness among farmers and veterinarians concerning the detection and reporting of FMD at an early stage of an outbreak for FMD control in Denmark. MDPI 2023-03-09 /pmc/articles/PMC10056164/ /pubmed/36986357 http://dx.doi.org/10.3390/pathogens12030435 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Conrady, Beate
Mortensen, Sten
Nielsen, Søren Saxmose
Houe, Hans
Calvo-Artavia, Francisco Fernando
Ellis-Iversen, Johanne
Boklund, Anette
Simulation of Foot-and-Mouth Disease Spread and Effects of Mitigation Strategies to Support Veterinary Contingency Planning in Denmark
title Simulation of Foot-and-Mouth Disease Spread and Effects of Mitigation Strategies to Support Veterinary Contingency Planning in Denmark
title_full Simulation of Foot-and-Mouth Disease Spread and Effects of Mitigation Strategies to Support Veterinary Contingency Planning in Denmark
title_fullStr Simulation of Foot-and-Mouth Disease Spread and Effects of Mitigation Strategies to Support Veterinary Contingency Planning in Denmark
title_full_unstemmed Simulation of Foot-and-Mouth Disease Spread and Effects of Mitigation Strategies to Support Veterinary Contingency Planning in Denmark
title_short Simulation of Foot-and-Mouth Disease Spread and Effects of Mitigation Strategies to Support Veterinary Contingency Planning in Denmark
title_sort simulation of foot-and-mouth disease spread and effects of mitigation strategies to support veterinary contingency planning in denmark
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056164/
https://www.ncbi.nlm.nih.gov/pubmed/36986357
http://dx.doi.org/10.3390/pathogens12030435
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