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Differential CMS-Related Expression of Cell Surface Carbonic Anhydrases IX and XII in Colorectal Cancer Models—Implications for Therapy

Tumor-associated carbonic anhydrases IX (CAIX) and XII (CAXII) have long been in the spotlight as potential new targets for anti-cancer therapy. Recently, CAIX/CAXII specific inhibitor SLC-0111 has passed clinical phase I study and showed differential response among patients with colorectal cancer (...

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Detalles Bibliográficos
Autores principales: Rotermund, Arne, Brandt, Sarah, Staege, Martin S., Luetzkendorf, Jana, Mueller, Lutz P., Mueller, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056265/
https://www.ncbi.nlm.nih.gov/pubmed/36982873
http://dx.doi.org/10.3390/ijms24065797

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