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Raman Spectroscopy for Early Detection of Cervical Cancer, a Global Women’s Health Issue—A Review
This review focuses on recent advances and future perspectives in the use of Raman spectroscopy for cervical cancer, a global women’s health issue. Cervical cancer is the fourth most common women’s cancer in the world, and unfortunately mainly affects younger women. However, when detected at the ear...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056388/ https://www.ncbi.nlm.nih.gov/pubmed/36985474 http://dx.doi.org/10.3390/molecules28062502 |
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author | Shaikh, Rubina Daniel, Amuthachelvi Lyng, Fiona M. |
author_facet | Shaikh, Rubina Daniel, Amuthachelvi Lyng, Fiona M. |
author_sort | Shaikh, Rubina |
collection | PubMed |
description | This review focuses on recent advances and future perspectives in the use of Raman spectroscopy for cervical cancer, a global women’s health issue. Cervical cancer is the fourth most common women’s cancer in the world, and unfortunately mainly affects younger women. However, when detected at the early precancer stage, it is highly treatable. High-quality cervical screening programmes and the introduction of the human papillomavirus (HPV) vaccine are reducing the incidence of cervical cancer in many countries, but screening is still essential for all women. Current gold standard methods include HPV testing and cytology for screening, followed by colposcopy and histopathology for diagnosis. However, these methods are limited in terms of sensitivity/specificity, cost, and time. New methods are required to aid clinicians in the early detection of cervical precancer. Over the past 20 years, the potential of Raman spectroscopy together with multivariate statistical analysis has been shown for the detection of cervical cancer. This review discusses the research to date on Raman spectroscopic approaches for cervical cancer using exfoliated cells, biofluid samples, and tissue ex vivo and in vivo. |
format | Online Article Text |
id | pubmed-10056388 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-100563882023-03-30 Raman Spectroscopy for Early Detection of Cervical Cancer, a Global Women’s Health Issue—A Review Shaikh, Rubina Daniel, Amuthachelvi Lyng, Fiona M. Molecules Review This review focuses on recent advances and future perspectives in the use of Raman spectroscopy for cervical cancer, a global women’s health issue. Cervical cancer is the fourth most common women’s cancer in the world, and unfortunately mainly affects younger women. However, when detected at the early precancer stage, it is highly treatable. High-quality cervical screening programmes and the introduction of the human papillomavirus (HPV) vaccine are reducing the incidence of cervical cancer in many countries, but screening is still essential for all women. Current gold standard methods include HPV testing and cytology for screening, followed by colposcopy and histopathology for diagnosis. However, these methods are limited in terms of sensitivity/specificity, cost, and time. New methods are required to aid clinicians in the early detection of cervical precancer. Over the past 20 years, the potential of Raman spectroscopy together with multivariate statistical analysis has been shown for the detection of cervical cancer. This review discusses the research to date on Raman spectroscopic approaches for cervical cancer using exfoliated cells, biofluid samples, and tissue ex vivo and in vivo. MDPI 2023-03-09 /pmc/articles/PMC10056388/ /pubmed/36985474 http://dx.doi.org/10.3390/molecules28062502 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Shaikh, Rubina Daniel, Amuthachelvi Lyng, Fiona M. Raman Spectroscopy for Early Detection of Cervical Cancer, a Global Women’s Health Issue—A Review |
title | Raman Spectroscopy for Early Detection of Cervical Cancer, a Global Women’s Health Issue—A Review |
title_full | Raman Spectroscopy for Early Detection of Cervical Cancer, a Global Women’s Health Issue—A Review |
title_fullStr | Raman Spectroscopy for Early Detection of Cervical Cancer, a Global Women’s Health Issue—A Review |
title_full_unstemmed | Raman Spectroscopy for Early Detection of Cervical Cancer, a Global Women’s Health Issue—A Review |
title_short | Raman Spectroscopy for Early Detection of Cervical Cancer, a Global Women’s Health Issue—A Review |
title_sort | raman spectroscopy for early detection of cervical cancer, a global women’s health issue—a review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056388/ https://www.ncbi.nlm.nih.gov/pubmed/36985474 http://dx.doi.org/10.3390/molecules28062502 |
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