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α-Hederin Saponin Augments the Chemopreventive Effect of Cisplatin against Ehrlich Tumors and Bioinformatic Approach Identifying the Role of SDF1/CXCR4/p-AKT-1/NFκB Signaling
Stromal cell-derived factor-1 (SDF1) and its C-X-C chemokine receptor type 4 receptor (CXCR4) are significant mediators for cancer cells’ proliferation, and we studied their expression in Ehrlich solid tumors (ESTs) grown in mice. α-Hederin is a pentacyclic triterpenoid saponin found in Hedera or Ni...
Autores principales: | Elaidy, Samah M., El-Kherbetawy, Mohamed K., Abed, Sally Y., Alattar, Abdullah, Alshaman, Reem, Eladl, Mohamed Ahmed, Alamri, Eman Saad, Al balawi, Aisha Nawaf, Zaid, AbdelNaser, Elkazzaz, Amany Y., Abdelkhalig, Sozan M., Hamed, Ziad E., Zaitone, Sawsan A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056433/ https://www.ncbi.nlm.nih.gov/pubmed/36986504 http://dx.doi.org/10.3390/ph16030405 |
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