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Post-COVID-19 Fungal Infection in the Aged Population
Coronavirus disease 2019 (COVID-19) infection is currently a great cause of concern for the healthcare sector around the globe. SARS-CoV-2 is an RNA virus that causes a serious infection that is associated with numerous adverse effects and multiple complications associated with different organs and...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056493/ https://www.ncbi.nlm.nih.gov/pubmed/36992139 http://dx.doi.org/10.3390/vaccines11030555 |
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author | Chavda, Vivek P. Mishra, Toshika Kamaraj, Sathvika Punetha, Swati Sengupta, Oishani Joshi, Yash Vuppu, Suneetha Vaghela, Dixa Vora, Lalitkumar |
author_facet | Chavda, Vivek P. Mishra, Toshika Kamaraj, Sathvika Punetha, Swati Sengupta, Oishani Joshi, Yash Vuppu, Suneetha Vaghela, Dixa Vora, Lalitkumar |
author_sort | Chavda, Vivek P. |
collection | PubMed |
description | Coronavirus disease 2019 (COVID-19) infection is currently a great cause of concern for the healthcare sector around the globe. SARS-CoV-2 is an RNA virus that causes a serious infection that is associated with numerous adverse effects and multiple complications associated with different organs and systems during its pathogenic cycle in humans. Individuals affected by COVID-19, especially elderly populations and immunocompromised people, are greatly vulnerable to opportunistic fungal pathogens. Aspergillosis, invasive candidiasis, and mucormycosis are widespread fungal coinfections in COVID-19 patients. Other fungal infections that are rare but are exhibiting increased incidence in the current scenario include infections caused by Pneumocystis jirovecii, Histoplasma sp., Cryptococcus sp., etc. By producing virulent spores, these pathogens increase the severity of the disease and increase the morbidity and fatality rates in COVID-19 patients globally. These infections generally occur in patients recovering from COVID-19 infection, resulting in rehospitalization. Older and immunocompromised individuals are at higher risk of developing opportunistic fungal infections. This review focuses on understanding the opportunistic fungal infections prevalent in COVID-19 patients, especially elderly people. We have also highlighted the important preventive methods, diagnostic approaches, and prophylactic measures for fungal infections. |
format | Online Article Text |
id | pubmed-10056493 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-100564932023-03-30 Post-COVID-19 Fungal Infection in the Aged Population Chavda, Vivek P. Mishra, Toshika Kamaraj, Sathvika Punetha, Swati Sengupta, Oishani Joshi, Yash Vuppu, Suneetha Vaghela, Dixa Vora, Lalitkumar Vaccines (Basel) Review Coronavirus disease 2019 (COVID-19) infection is currently a great cause of concern for the healthcare sector around the globe. SARS-CoV-2 is an RNA virus that causes a serious infection that is associated with numerous adverse effects and multiple complications associated with different organs and systems during its pathogenic cycle in humans. Individuals affected by COVID-19, especially elderly populations and immunocompromised people, are greatly vulnerable to opportunistic fungal pathogens. Aspergillosis, invasive candidiasis, and mucormycosis are widespread fungal coinfections in COVID-19 patients. Other fungal infections that are rare but are exhibiting increased incidence in the current scenario include infections caused by Pneumocystis jirovecii, Histoplasma sp., Cryptococcus sp., etc. By producing virulent spores, these pathogens increase the severity of the disease and increase the morbidity and fatality rates in COVID-19 patients globally. These infections generally occur in patients recovering from COVID-19 infection, resulting in rehospitalization. Older and immunocompromised individuals are at higher risk of developing opportunistic fungal infections. This review focuses on understanding the opportunistic fungal infections prevalent in COVID-19 patients, especially elderly people. We have also highlighted the important preventive methods, diagnostic approaches, and prophylactic measures for fungal infections. MDPI 2023-02-27 /pmc/articles/PMC10056493/ /pubmed/36992139 http://dx.doi.org/10.3390/vaccines11030555 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Chavda, Vivek P. Mishra, Toshika Kamaraj, Sathvika Punetha, Swati Sengupta, Oishani Joshi, Yash Vuppu, Suneetha Vaghela, Dixa Vora, Lalitkumar Post-COVID-19 Fungal Infection in the Aged Population |
title | Post-COVID-19 Fungal Infection in the Aged Population |
title_full | Post-COVID-19 Fungal Infection in the Aged Population |
title_fullStr | Post-COVID-19 Fungal Infection in the Aged Population |
title_full_unstemmed | Post-COVID-19 Fungal Infection in the Aged Population |
title_short | Post-COVID-19 Fungal Infection in the Aged Population |
title_sort | post-covid-19 fungal infection in the aged population |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056493/ https://www.ncbi.nlm.nih.gov/pubmed/36992139 http://dx.doi.org/10.3390/vaccines11030555 |
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