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Advances in TB testing

Globally, tuberculosis (TB) was the leading cause of death from a single infectious agent until the coronavirus (COVID-19) pandemic. In 2020, an estimated 10 million people fell ill with TB and a total of 1.5 million people died from the disease. About one-quarter of the global population, almost tw...

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Detalles Bibliográficos
Autores principales: Pagaduan, Jayson V., Altawallbeh, Ghaith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056534/
https://www.ncbi.nlm.nih.gov/pubmed/37673521
http://dx.doi.org/10.1016/bs.acc.2023.03.003
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author Pagaduan, Jayson V.
Altawallbeh, Ghaith
author_facet Pagaduan, Jayson V.
Altawallbeh, Ghaith
author_sort Pagaduan, Jayson V.
collection PubMed
description Globally, tuberculosis (TB) was the leading cause of death from a single infectious agent until the coronavirus (COVID-19) pandemic. In 2020, an estimated 10 million people fell ill with TB and a total of 1.5 million people died from the disease. About one-quarter of the global population, almost two billion people, is estimated to be latently infected with Mycobacterium tuberculosis (MTB). Although latent TB infection (LTBI) is asymptomatic and noncontagious, about 5–10% of LTBI patients have a lifetime risk of progression to active TB. The diagnosis and treatment of active cases are extremely vital for TB control programs. However, achieving the End TB goal of 2035 without the ability to identify and treat the pool of latently infected individuals will be a big challenge. To do so, improved technology to provide more accurate diagnostic tools and accessibility are crucial. Therefore, this chapter covers the current WHO-endorsed tests and advances in diagnostic and screening tests for active and latent TB.
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spelling pubmed-100565342023-03-30 Advances in TB testing Pagaduan, Jayson V. Altawallbeh, Ghaith Adv Clin Chem Article Globally, tuberculosis (TB) was the leading cause of death from a single infectious agent until the coronavirus (COVID-19) pandemic. In 2020, an estimated 10 million people fell ill with TB and a total of 1.5 million people died from the disease. About one-quarter of the global population, almost two billion people, is estimated to be latently infected with Mycobacterium tuberculosis (MTB). Although latent TB infection (LTBI) is asymptomatic and noncontagious, about 5–10% of LTBI patients have a lifetime risk of progression to active TB. The diagnosis and treatment of active cases are extremely vital for TB control programs. However, achieving the End TB goal of 2035 without the ability to identify and treat the pool of latently infected individuals will be a big challenge. To do so, improved technology to provide more accurate diagnostic tools and accessibility are crucial. Therefore, this chapter covers the current WHO-endorsed tests and advances in diagnostic and screening tests for active and latent TB. Published by Elsevier Ltd. 2023-03-29 /pmc/articles/PMC10056534/ /pubmed/37673521 http://dx.doi.org/10.1016/bs.acc.2023.03.003 Text en Copyright © 2023 Published by Elsevier Ltd. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Pagaduan, Jayson V.
Altawallbeh, Ghaith
Advances in TB testing
title Advances in TB testing
title_full Advances in TB testing
title_fullStr Advances in TB testing
title_full_unstemmed Advances in TB testing
title_short Advances in TB testing
title_sort advances in tb testing
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056534/
https://www.ncbi.nlm.nih.gov/pubmed/37673521
http://dx.doi.org/10.1016/bs.acc.2023.03.003
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