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Ex Vivo Visualization of Distribution of Intravitreal Injections in the Porcine Vitreous and Hydrogels Simulating the Vitreous
The characterization of intravitreal dosage forms with regard to their behavior in vivo is usually explored in preclinical development through animal studies. In vitro vitreous substitutes (VS) to simulate the vitreous body for preclinical investigations have so far been insufficiently studied. To d...
Autores principales: | Auel, Tobias, Scherke, Lara Paula, Hadlich, Stefan, Mouchantat, Susan, Grimm, Michael, Weitschies, Werner, Seidlitz, Anne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056607/ https://www.ncbi.nlm.nih.gov/pubmed/36986647 http://dx.doi.org/10.3390/pharmaceutics15030786 |
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