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Approaching Artificial Intelligence in Orthopaedics: Predictive Analytics and Machine Learning to Prognosticate Arthroscopic Rotator Cuff Surgical Outcomes

Machine learning (ML) has not yet been used to identify factors predictive for post-operative functional outcomes following arthroscopic rotator cuff repair (ARCR). We propose a novel algorithm to predict ARCR outcomes using machine learning. This is a retrospective cohort study from a prospectively...

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Autores principales: Potty, Anish G., Potty, Ajish S. R., Maffulli, Nicola, Blumenschein, Lucas A., Ganta, Deepak, Mistovich, R. Justin, Fuentes, Mario, Denard, Patrick J., Sethi, Paul M., Shah, Anup A., Gupta, Ashim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056706/
https://www.ncbi.nlm.nih.gov/pubmed/36983368
http://dx.doi.org/10.3390/jcm12062369
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author Potty, Anish G.
Potty, Ajish S. R.
Maffulli, Nicola
Blumenschein, Lucas A.
Ganta, Deepak
Mistovich, R. Justin
Fuentes, Mario
Denard, Patrick J.
Sethi, Paul M.
Shah, Anup A.
Gupta, Ashim
author_facet Potty, Anish G.
Potty, Ajish S. R.
Maffulli, Nicola
Blumenschein, Lucas A.
Ganta, Deepak
Mistovich, R. Justin
Fuentes, Mario
Denard, Patrick J.
Sethi, Paul M.
Shah, Anup A.
Gupta, Ashim
author_sort Potty, Anish G.
collection PubMed
description Machine learning (ML) has not yet been used to identify factors predictive for post-operative functional outcomes following arthroscopic rotator cuff repair (ARCR). We propose a novel algorithm to predict ARCR outcomes using machine learning. This is a retrospective cohort study from a prospectively collected database. Data were collected from the Surgical Outcome System Global Registry (Arthrex, Naples, FL, USA). Pre-operative and 3-month, 6-month, and 12-month post-operative American Shoulder and Elbow Surgeons (ASES) scores were collected and used to develop a ML model. Pre-operative factors including demography, comorbidities, cuff tear, tissue quality, and fixation implants were fed to the ML model. The algorithm then produced an expected post-operative ASES score for each patient. The ML-produced scores were compared to actual scores using standard test-train machine learning principles. Overall, 631 patients who underwent shoulder arthroscopy from January 2011 to March 2020 met inclusion criteria for final analysis. A substantial number of the test dataset predictions using the XGBoost algorithm were within the minimal clinically important difference (MCID) and substantial clinical benefit (SCB) thresholds: 67% of the 12-month post-operative predictions were within MCID, while 84% were within SCB. Pre-operative ASES score, pre-operative pain score, body mass index (BMI), age, and tendon quality were the most important features in predicting patient recovery as identified using Shapley additive explanations (SHAP). In conclusion, the proposed novel machine learning algorithm can use pre-operative factors to predict post-operative ASES scores accurately. This can further supplement pre-operative counselling, planning, and resource allocation. Level of Evidence: III.
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spelling pubmed-100567062023-03-30 Approaching Artificial Intelligence in Orthopaedics: Predictive Analytics and Machine Learning to Prognosticate Arthroscopic Rotator Cuff Surgical Outcomes Potty, Anish G. Potty, Ajish S. R. Maffulli, Nicola Blumenschein, Lucas A. Ganta, Deepak Mistovich, R. Justin Fuentes, Mario Denard, Patrick J. Sethi, Paul M. Shah, Anup A. Gupta, Ashim J Clin Med Article Machine learning (ML) has not yet been used to identify factors predictive for post-operative functional outcomes following arthroscopic rotator cuff repair (ARCR). We propose a novel algorithm to predict ARCR outcomes using machine learning. This is a retrospective cohort study from a prospectively collected database. Data were collected from the Surgical Outcome System Global Registry (Arthrex, Naples, FL, USA). Pre-operative and 3-month, 6-month, and 12-month post-operative American Shoulder and Elbow Surgeons (ASES) scores were collected and used to develop a ML model. Pre-operative factors including demography, comorbidities, cuff tear, tissue quality, and fixation implants were fed to the ML model. The algorithm then produced an expected post-operative ASES score for each patient. The ML-produced scores were compared to actual scores using standard test-train machine learning principles. Overall, 631 patients who underwent shoulder arthroscopy from January 2011 to March 2020 met inclusion criteria for final analysis. A substantial number of the test dataset predictions using the XGBoost algorithm were within the minimal clinically important difference (MCID) and substantial clinical benefit (SCB) thresholds: 67% of the 12-month post-operative predictions were within MCID, while 84% were within SCB. Pre-operative ASES score, pre-operative pain score, body mass index (BMI), age, and tendon quality were the most important features in predicting patient recovery as identified using Shapley additive explanations (SHAP). In conclusion, the proposed novel machine learning algorithm can use pre-operative factors to predict post-operative ASES scores accurately. This can further supplement pre-operative counselling, planning, and resource allocation. Level of Evidence: III. MDPI 2023-03-19 /pmc/articles/PMC10056706/ /pubmed/36983368 http://dx.doi.org/10.3390/jcm12062369 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Potty, Anish G.
Potty, Ajish S. R.
Maffulli, Nicola
Blumenschein, Lucas A.
Ganta, Deepak
Mistovich, R. Justin
Fuentes, Mario
Denard, Patrick J.
Sethi, Paul M.
Shah, Anup A.
Gupta, Ashim
Approaching Artificial Intelligence in Orthopaedics: Predictive Analytics and Machine Learning to Prognosticate Arthroscopic Rotator Cuff Surgical Outcomes
title Approaching Artificial Intelligence in Orthopaedics: Predictive Analytics and Machine Learning to Prognosticate Arthroscopic Rotator Cuff Surgical Outcomes
title_full Approaching Artificial Intelligence in Orthopaedics: Predictive Analytics and Machine Learning to Prognosticate Arthroscopic Rotator Cuff Surgical Outcomes
title_fullStr Approaching Artificial Intelligence in Orthopaedics: Predictive Analytics and Machine Learning to Prognosticate Arthroscopic Rotator Cuff Surgical Outcomes
title_full_unstemmed Approaching Artificial Intelligence in Orthopaedics: Predictive Analytics and Machine Learning to Prognosticate Arthroscopic Rotator Cuff Surgical Outcomes
title_short Approaching Artificial Intelligence in Orthopaedics: Predictive Analytics and Machine Learning to Prognosticate Arthroscopic Rotator Cuff Surgical Outcomes
title_sort approaching artificial intelligence in orthopaedics: predictive analytics and machine learning to prognosticate arthroscopic rotator cuff surgical outcomes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056706/
https://www.ncbi.nlm.nih.gov/pubmed/36983368
http://dx.doi.org/10.3390/jcm12062369
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