Cargando…

Apelin Is a Prototype of Novel Drugs for the Treatment of Acute Myocardial Infarction and Adverse Myocardial Remodeling

In-hospital mortality in patients with ST-segment elevation myocardial infarction (STEMI) is 5–6%. Consequently, it is necessary to develop fundamentally novel drugs capable of reducing mortality in patients with acute myocardial infarction. Apelins could be the prototype for such drugs. Chronic adm...

Descripción completa

Detalles Bibliográficos
Autores principales:	Popov, Sergey V., Maslov, Leonid N., Mukhomedzyanov, Alexandr V., Kurbatov, Boris K., Gorbunov, Alexandr S., Kilin, Michail, Azev, Viacheslav N., Khlestkina, Maria S., Sufianova, Galina Z.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056827/ https://www.ncbi.nlm.nih.gov/pubmed/36986889 http://dx.doi.org/10.3390/pharmaceutics15031029

Ejemplares similares

The Infarct-Reducing Effect of the δ(2) Opioid Receptor Agonist Deltorphin II: The Molecular Mechanism
por: Popov, Sergey V., et al.
Publicado: (2023)

Pharmacological Approaches to Limit Ischemic and Reperfusion Injuries of the Heart: Analysis of Experimental and Clinical Data on P2Y(12) Receptor Antagonists
por: Maslov, Leonid N., et al.
Publicado: (2022)

Do reactive oxygen species damage or protect the heart in ischemia and reperfusion? Analysis on experimental and clinical data
por: Maslov, Leonid N., et al.
Publicado: (2023)

A historical literature review of coronary microvascular obstruction and intra-myocardial hemorrhage as functional/structural phenomena
por: Maslov, Leonid N., et al.
Publicado: (2023)

δ-Opioid Receptor as a Molecular Target for Increasing Cardiac Resistance to Reperfusion in Drug Development
por: Naryzhnaya, Natalia V., et al.
Publicado: (2023)

The Signaling Mechanism of Remote Postconditioning of the Heart: Prospects of the Use of Remote Postconditioning for the Treatment of Acute Myocardial Infarction
por: Ryabov, Vyacheslav V., et al.
Publicado: (2023)

Pyroptosis is a drug target for prevention of adverse cardiac remodeling: The crosstalk between pyroptosis, apoptosis, and autophagy
por: Naryzhnaya, Natalia V., et al.
Publicado: (2022)

Loss of Apelin Exacerbates Myocardial Infarction Adverse Remodeling and Ischemia‐reperfusion Injury: Therapeutic Potential of Synthetic Apelin Analogues
por: Wang, Wang, et al.
Publicado: (2013)

Effects of structural analogues of apelin-12 in acute myocardial infarction in rats
por: Pisarenko, Oleg I., et al.
Publicado: (2013)

Reperfusion Cardiac Injury: Receptors and the Signaling Mechanisms
por: Maslov, Leonid N., et al.
Publicado: (2022)

Apelin-12 and its structural analog enhance antioxidant defense in experimental myocardial ischemia and reperfusion
por: Pisarenko, O. I., et al.
Publicado: (2014)

Left ventricular myocardial remodeling in dogs with mitral valve endocardiosis
por: Vatnikov, Yury A., et al.
Publicado: (2020)

Sirt3 is essential for apelin-induced angiogenesis in post-myocardial infarction of diabetes
por: Hou, Xuwei, et al.
Publicado: (2015)

Ischemic heart failure enhances endogenous myocardial apelin and APJ receptor expression
por: Atluri, Pavan, et al.
Publicado: (2006)

The role of air pollution in myocardial remodeling
por: de Oliveira-Fonoff, A. M., et al.
Publicado: (2017)

Apelin protects against myocardial ischemic injury by inhibiting dynamin-related protein 1
por: Xu, Wei, et al.
Publicado: (2017)

Myocardial Injection of Apelin-Overexpressing Bone Marrow Cells Improves Cardiac Repair via Upregulation of Sirt3 after Myocardial Infarction
por: Li, Lanfang, et al.
Publicado: (2013)

Structural apelin analogues: mitochondrial ROS inhibition and cardiometabolic protection in myocardial ischaemia reperfusion injury
por: Pisarenko, Oleg, et al.
Publicado: (2015)

Apelin regulates FoxO3 translocation to mediate cardioprotective responses to myocardial injury and obesity
por: Boal, Frederic, et al.
Publicado: (2015)

Plasma apelin level in acute myocardial infarction and its relation with prognosis: A prospective study
por: Guzelburc, Ozge, et al.
Publicado: (2021)

Physiological and Pathological Role of TRPV1, TRPV2 and TRPV4 Channels in Heart
por: Gorbunov, Alexandr S., et al.
Publicado: (2019)

Myocardial Tissue Remodeling in Adolescent Obesity
por: Shah, Ravi V., et al.
Publicado: (2013)

Takotsubo Syndrome: Clinical Manifestations, Etiology and Pathogenesis
por: Prokudina, Ekaterina S., et al.
Publicado: (2021)

Relationship of Acylcarnitines to Myocardial Ischemic Remodeling and Clinical Manifestations in Chronic Heart Failure
por: Belenkov, Yuri N., et al.
Publicado: (2023)

Apelin and vascular endothelial growth factor are associated with mobilization of endothelial progenitor cells after acute myocardial infarction
por: Ye, Jiaxin, et al.
Publicado: (2012)

0100. Apelin is cardioprotective and life-saving over dobutamine in a murine model of endotoxin-induced myocardial dysfunction
por: Lesur, O, et al.
Publicado: (2014)

Apelin-13 Pretreatment Promotes the Cardioprotective Effect of Mesenchymal Stem Cells against Myocardial Infarction by Improving Their Survival
por: Chen, Guona, et al.
Publicado: (2022)

Lymphangiogenesis in myocardial remodelling after infarction
por: Ishikawa, Y, et al.
Publicado: (2007)

Effect of ouabain on myocardial remodeling in rats
por: REN, YANPING, et al.
Publicado: (2013)

Electrical and Myocardial Remodeling in Primary Aldosteronism
por: Curione, Mario, et al.
Publicado: (2014)

Myocardial remodelling and recovery in dilated cardiomyopathy
por: Tayal, Upasana, et al.
Publicado: (2017)

Fimasartan for Remodeling after Myocardial Infarction
por: Lim, Byung-Kwan, et al.
Publicado: (2019)

On Methods for the Measurement of the Apelin Receptor Ligand Apelin
por: Janssens, Peter, et al.
Publicado: (2022)

Effect of Wenxin Granule on Ventricular Remodeling and Myocardial Apoptosis in Rats with Myocardial Infarction
por: Wu, Aiming, et al.
Publicado: (2013)

Metformin attenuates myocardial remodeling and neutrophil recruitment after myocardial infarction in rat
por: Soraya, Hamid, et al.
Publicado: (2015)

Regulation of Myocardial Extracellular Matrix Dynamic Changes in Myocardial Infarction and Postinfarct Remodeling
por: Ushakov, Alexey, et al.
Publicado: (2020)

Myocardial TGFβ2 Is Required for Atrioventricular Cushion Remodeling and Myocardial Development
por: Bhattacharya, Aniket, et al.
Publicado: (2021)

Loss of Apelin Augments Angiotensin II-Induced Cardiac Dysfunction and Pathological Remodeling
por: Sato, Teruki, et al.
Publicado: (2019)

Apelin and apelin receptor expression in renal cell carcinoma
por: Tolkach, Yuri, et al.
Publicado: (2019)

Prognostic Value of Combining Apelin-12 and Estimated Glomerular Filtration Rate in Patients with ST-Segment Elevation Myocardial Infarction
por: Liu, Yue, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_4tjaskgmla0carktg2a4m9tugn