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Hyaluronidase Promote Transdermal Diffusion of Small Sized Curcumin Nanocrystal by Dissolving Microneedles Delivery
Hyaluronidase is clinically used in treating many skin diseases due to its good permeability-promoting effect, which may motivate the diffusion and absorption of drugs. To verify the penetration osmotic effect of hyaluronidase in microneedles, 55 nm-size curcumin nanocrystals were fabricated and loa...
Autores principales: | Miao, Xiaoqing, Zhao, Jingru, Xiang, Hong, Shi, Xiaoxi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056829/ https://www.ncbi.nlm.nih.gov/pubmed/36986649 http://dx.doi.org/10.3390/pharmaceutics15030788 |
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