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Bovine Grafting: An Effective Alternative after Curettage of Benign Bone Tumors

We retrospectively reviewed 28 patients (15 women and 13 men) with benign bone tumors or pseudotumors treated with curettage and filling with freeze-dried bovine bone graft Orthogen (Baumer S/A, São Paulo, Brazil). The aim of the study was to evaluate the rate of incorporation of Orthogen into the h...

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Autores principales: Montanhini, Priscilla, Antunes, Bruno P., Pestilho, Julie Francine Cerutti, Galia, Carlos Roberto, Guedes, Alex, Becker, Ricardo Gehrke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056842/
https://www.ncbi.nlm.nih.gov/pubmed/36983944
http://dx.doi.org/10.3390/life13030789
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author Montanhini, Priscilla
Antunes, Bruno P.
Pestilho, Julie Francine Cerutti
Galia, Carlos Roberto
Guedes, Alex
Becker, Ricardo Gehrke
author_facet Montanhini, Priscilla
Antunes, Bruno P.
Pestilho, Julie Francine Cerutti
Galia, Carlos Roberto
Guedes, Alex
Becker, Ricardo Gehrke
author_sort Montanhini, Priscilla
collection PubMed
description We retrospectively reviewed 28 patients (15 women and 13 men) with benign bone tumors or pseudotumors treated with curettage and filling with freeze-dried bovine bone graft Orthogen (Baumer S/A, São Paulo, Brazil). The aim of the study was to evaluate the rate of incorporation of Orthogen into the host bone, as well as to describe the outcomes of bone healing (quality, time, and complications). General characteristics, tumor volume, size, site, complications, percent filled, and healing quality at 6 and 12 months were assessed through radiographs. Mean patient age was 20.5 (range 4.7–75.1) years. The most common lesion type was simple bone cyst (12/28), and the most common sites were the tibia (7/28) and humerus (7/28). There were no postoperative pathologic fractures. Two cases (7.1%) of serous fluid leakage through the wound occurred. Mean cavity volume was 20.1 (range 2.7–101.4) cm(3). At 6 and 12 months, 75% and 77.8% of cavities, respectively, showed complete bone healing. At 12 months, 81% of cavities filled >90% with graft showed complete bone healing vs. only 19% of those filled <90%. Filling with bovine bone graft resulted in few complications and excellent healing after curettage of benign bone tumors or pseudotumors. Complete healing occurred in most cases by 12 months. Cavities with a higher percentage of filling had a higher rate of complete radiographic incorporation.
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spelling pubmed-100568422023-03-30 Bovine Grafting: An Effective Alternative after Curettage of Benign Bone Tumors Montanhini, Priscilla Antunes, Bruno P. Pestilho, Julie Francine Cerutti Galia, Carlos Roberto Guedes, Alex Becker, Ricardo Gehrke Life (Basel) Communication We retrospectively reviewed 28 patients (15 women and 13 men) with benign bone tumors or pseudotumors treated with curettage and filling with freeze-dried bovine bone graft Orthogen (Baumer S/A, São Paulo, Brazil). The aim of the study was to evaluate the rate of incorporation of Orthogen into the host bone, as well as to describe the outcomes of bone healing (quality, time, and complications). General characteristics, tumor volume, size, site, complications, percent filled, and healing quality at 6 and 12 months were assessed through radiographs. Mean patient age was 20.5 (range 4.7–75.1) years. The most common lesion type was simple bone cyst (12/28), and the most common sites were the tibia (7/28) and humerus (7/28). There were no postoperative pathologic fractures. Two cases (7.1%) of serous fluid leakage through the wound occurred. Mean cavity volume was 20.1 (range 2.7–101.4) cm(3). At 6 and 12 months, 75% and 77.8% of cavities, respectively, showed complete bone healing. At 12 months, 81% of cavities filled >90% with graft showed complete bone healing vs. only 19% of those filled <90%. Filling with bovine bone graft resulted in few complications and excellent healing after curettage of benign bone tumors or pseudotumors. Complete healing occurred in most cases by 12 months. Cavities with a higher percentage of filling had a higher rate of complete radiographic incorporation. MDPI 2023-03-15 /pmc/articles/PMC10056842/ /pubmed/36983944 http://dx.doi.org/10.3390/life13030789 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Montanhini, Priscilla
Antunes, Bruno P.
Pestilho, Julie Francine Cerutti
Galia, Carlos Roberto
Guedes, Alex
Becker, Ricardo Gehrke
Bovine Grafting: An Effective Alternative after Curettage of Benign Bone Tumors
title Bovine Grafting: An Effective Alternative after Curettage of Benign Bone Tumors
title_full Bovine Grafting: An Effective Alternative after Curettage of Benign Bone Tumors
title_fullStr Bovine Grafting: An Effective Alternative after Curettage of Benign Bone Tumors
title_full_unstemmed Bovine Grafting: An Effective Alternative after Curettage of Benign Bone Tumors
title_short Bovine Grafting: An Effective Alternative after Curettage of Benign Bone Tumors
title_sort bovine grafting: an effective alternative after curettage of benign bone tumors
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056842/
https://www.ncbi.nlm.nih.gov/pubmed/36983944
http://dx.doi.org/10.3390/life13030789
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