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Human Brain Microvascular Endothelial Cells Exposure to SARS-CoV-2 Leads to Inflammatory Activation through NF-κB Non-Canonical Pathway and Mitochondrial Remodeling

Neurological effects of COVID-19 and long-COVID-19, as well as neuroinvasion by SARS-CoV-2, still pose several questions and are of both clinical and scientific relevance. We described the cellular and molecular effects of the human brain microvascular endothelial cells (HBMECs) in vitro exposure by...

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Detalles Bibliográficos
Autores principales: Motta, Carolline Soares, Torices, Silvia, da Rosa, Barbara Gomes, Marcos, Anne Caroline, Alvarez-Rosa, Liandra, Siqueira, Michele, Moreno-Rodriguez, Thaidy, Matos, Aline da Rocha, Caetano, Braulia Costa, Martins, Jessica Santa Cruz de Carvalho, Gladulich, Luis, Loiola, Erick, Bagshaw, Olivia R. M., Stuart, Jeffrey A., Siqueira, Marilda M., Stipursky, Joice, Toborek, Michal, Adesse, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10056985/
https://www.ncbi.nlm.nih.gov/pubmed/36992454
http://dx.doi.org/10.3390/v15030745