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Follow-Up of Side Effects throughout the Entire Course of Coronavirus Vaccination

Vaccines are considered the best protective means against coronavirus infection. There is increasing interest in reporting the side effects of vaccines, especially for individuals younger than 18 years old. Accordingly, this analytical cohort study aims to report on the side effects of adult and you...

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Autores principales: Odeh, Mohanad, Al-Jussani, Ghada Nazar, Ashour, Abdelrahman, AlNaqah, Husam, Hasan, Hamza A., Sbitan, Lana, Dawabsheh, Amro, Alhawi, Moayad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10057026/
https://www.ncbi.nlm.nih.gov/pubmed/36992288
http://dx.doi.org/10.3390/vaccines11030704
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author Odeh, Mohanad
Al-Jussani, Ghada Nazar
Ashour, Abdelrahman
AlNaqah, Husam
Hasan, Hamza A.
Sbitan, Lana
Dawabsheh, Amro
Alhawi, Moayad
author_facet Odeh, Mohanad
Al-Jussani, Ghada Nazar
Ashour, Abdelrahman
AlNaqah, Husam
Hasan, Hamza A.
Sbitan, Lana
Dawabsheh, Amro
Alhawi, Moayad
author_sort Odeh, Mohanad
collection PubMed
description Vaccines are considered the best protective means against coronavirus infection. There is increasing interest in reporting the side effects of vaccines, especially for individuals younger than 18 years old. Accordingly, this analytical cohort study aims to report on the side effects of adult and young individuals who received vaccination within 24 h, 72 h, 5 days, and 1 week through the entire course of vaccination (ECoV). A validated online survey was used to collect information. In total, 1069 individuals were completely followed. Most individuals received the Pfizer vaccine (59.6%). Most individuals had received two doses (69.4%). Very strong and statistically significant associations with side effects (p < 0.05, Phi (Φ) > 0.25) throughout the ECoV were reported for the type of vaccine and female gender. Non-smokers reported weak statistically significant associations. Fatigue and localized pain were the most commonly reported side effect, with onset within 24 h and duration of less than 72 h. The prevalence of reported side effects was statistically significantly higher among young individuals (<18 years old) than among adults (X(2) (1) =7.6, p = 0.006. Phi φ = 0.11).
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spelling pubmed-100570262023-03-30 Follow-Up of Side Effects throughout the Entire Course of Coronavirus Vaccination Odeh, Mohanad Al-Jussani, Ghada Nazar Ashour, Abdelrahman AlNaqah, Husam Hasan, Hamza A. Sbitan, Lana Dawabsheh, Amro Alhawi, Moayad Vaccines (Basel) Article Vaccines are considered the best protective means against coronavirus infection. There is increasing interest in reporting the side effects of vaccines, especially for individuals younger than 18 years old. Accordingly, this analytical cohort study aims to report on the side effects of adult and young individuals who received vaccination within 24 h, 72 h, 5 days, and 1 week through the entire course of vaccination (ECoV). A validated online survey was used to collect information. In total, 1069 individuals were completely followed. Most individuals received the Pfizer vaccine (59.6%). Most individuals had received two doses (69.4%). Very strong and statistically significant associations with side effects (p < 0.05, Phi (Φ) > 0.25) throughout the ECoV were reported for the type of vaccine and female gender. Non-smokers reported weak statistically significant associations. Fatigue and localized pain were the most commonly reported side effect, with onset within 24 h and duration of less than 72 h. The prevalence of reported side effects was statistically significantly higher among young individuals (<18 years old) than among adults (X(2) (1) =7.6, p = 0.006. Phi φ = 0.11). MDPI 2023-03-20 /pmc/articles/PMC10057026/ /pubmed/36992288 http://dx.doi.org/10.3390/vaccines11030704 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Odeh, Mohanad
Al-Jussani, Ghada Nazar
Ashour, Abdelrahman
AlNaqah, Husam
Hasan, Hamza A.
Sbitan, Lana
Dawabsheh, Amro
Alhawi, Moayad
Follow-Up of Side Effects throughout the Entire Course of Coronavirus Vaccination
title Follow-Up of Side Effects throughout the Entire Course of Coronavirus Vaccination
title_full Follow-Up of Side Effects throughout the Entire Course of Coronavirus Vaccination
title_fullStr Follow-Up of Side Effects throughout the Entire Course of Coronavirus Vaccination
title_full_unstemmed Follow-Up of Side Effects throughout the Entire Course of Coronavirus Vaccination
title_short Follow-Up of Side Effects throughout the Entire Course of Coronavirus Vaccination
title_sort follow-up of side effects throughout the entire course of coronavirus vaccination
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10057026/
https://www.ncbi.nlm.nih.gov/pubmed/36992288
http://dx.doi.org/10.3390/vaccines11030704
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