Cargando…

Recent Developments in Mpox Prevention and Treatment Options

Human mpox is an emerging epidemic in the world. The monkey pox virus (MPXV) belongs to the same family of zoonotic Orthopoxviridae as that of the smallpox virus and exhibits similar clinical symptomology. Information regarding its diagnostics, disease epidemiology, surveillance, preventive methods,...

Descripción completa

Detalles Bibliográficos
Autores principales: Malik, Shiza, Ahmad, Tahir, Ahsan, Omar, Muhammad, Khalid, Waheed, Yasir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10057056/
https://www.ncbi.nlm.nih.gov/pubmed/36992085
http://dx.doi.org/10.3390/vaccines11030500
_version_ 1785016269672546304
author Malik, Shiza
Ahmad, Tahir
Ahsan, Omar
Muhammad, Khalid
Waheed, Yasir
author_facet Malik, Shiza
Ahmad, Tahir
Ahsan, Omar
Muhammad, Khalid
Waheed, Yasir
author_sort Malik, Shiza
collection PubMed
description Human mpox is an emerging epidemic in the world. The monkey pox virus (MPXV) belongs to the same family of zoonotic Orthopoxviridae as that of the smallpox virus and exhibits similar clinical symptomology. Information regarding its diagnostics, disease epidemiology, surveillance, preventive methods, and treatment strategies are being collated with time. The purpose of this review is to trace the recent events in the scientific platform that have defined new preventive and treatment strategies against mpox. A methodological approach has been used to gather data from the latest literature to comprehensively overview the emerging treatment options. The results portion will cover details regarding the prevention of mpox. It will also shed light on a brief description of contemporary vaccines and antiviral agents that have been evaluated for their treatment potential since the emergence of the mpox threat. These treatment options are setting the pace for controlling the widespread monkeypox infection. However, the limitations attached to these treatment strategies need to be tackled quickly to increase their efficacy so that they can be deployed on a large scale for the prevention of this epidemic becoming another pandemic in this decade.
format Online
Article
Text
id pubmed-10057056
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-100570562023-03-30 Recent Developments in Mpox Prevention and Treatment Options Malik, Shiza Ahmad, Tahir Ahsan, Omar Muhammad, Khalid Waheed, Yasir Vaccines (Basel) Review Human mpox is an emerging epidemic in the world. The monkey pox virus (MPXV) belongs to the same family of zoonotic Orthopoxviridae as that of the smallpox virus and exhibits similar clinical symptomology. Information regarding its diagnostics, disease epidemiology, surveillance, preventive methods, and treatment strategies are being collated with time. The purpose of this review is to trace the recent events in the scientific platform that have defined new preventive and treatment strategies against mpox. A methodological approach has been used to gather data from the latest literature to comprehensively overview the emerging treatment options. The results portion will cover details regarding the prevention of mpox. It will also shed light on a brief description of contemporary vaccines and antiviral agents that have been evaluated for their treatment potential since the emergence of the mpox threat. These treatment options are setting the pace for controlling the widespread monkeypox infection. However, the limitations attached to these treatment strategies need to be tackled quickly to increase their efficacy so that they can be deployed on a large scale for the prevention of this epidemic becoming another pandemic in this decade. MDPI 2023-02-21 /pmc/articles/PMC10057056/ /pubmed/36992085 http://dx.doi.org/10.3390/vaccines11030500 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Malik, Shiza
Ahmad, Tahir
Ahsan, Omar
Muhammad, Khalid
Waheed, Yasir
Recent Developments in Mpox Prevention and Treatment Options
title Recent Developments in Mpox Prevention and Treatment Options
title_full Recent Developments in Mpox Prevention and Treatment Options
title_fullStr Recent Developments in Mpox Prevention and Treatment Options
title_full_unstemmed Recent Developments in Mpox Prevention and Treatment Options
title_short Recent Developments in Mpox Prevention and Treatment Options
title_sort recent developments in mpox prevention and treatment options
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10057056/
https://www.ncbi.nlm.nih.gov/pubmed/36992085
http://dx.doi.org/10.3390/vaccines11030500
work_keys_str_mv AT malikshiza recentdevelopmentsinmpoxpreventionandtreatmentoptions
AT ahmadtahir recentdevelopmentsinmpoxpreventionandtreatmentoptions
AT ahsanomar recentdevelopmentsinmpoxpreventionandtreatmentoptions
AT muhammadkhalid recentdevelopmentsinmpoxpreventionandtreatmentoptions
AT waheedyasir recentdevelopmentsinmpoxpreventionandtreatmentoptions