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A Convenient Diels-Alder Approach toward Potential Polyketide-like Antibiotics Using α-Activated α,β-Unsaturated 4,4-Dimethyl-1-tetralones as Dienophiles
Making use of a Diels–Alder approach based on various α,β-unsaturated 2-carbomethoxy-4,4-dimethyl-1-tetralones as novel dienophiles, the corresponding polycyclic adducts could be efficiently synthesized in good to high yields (74~99%) in the presence of Lewis acid (e.g., SnCl(4)). Accordingly, a syn...
Autores principales: | Lee, Chia-Jui, Ramasamy, Manickavasakam, Kuan, Hsuan-Hao, Wu, Chien-Huang, Lee, Chein-Chung, Lee, Jinq-Chyi, Shia, Kak-Shan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10057133/ https://www.ncbi.nlm.nih.gov/pubmed/36985714 http://dx.doi.org/10.3390/molecules28062739 |
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