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Development of pH-Responsive N-benzyl-N-O-succinyl Chitosan Micelles Loaded with a Curcumin Analog (Cyqualone) for Treatment of Colon Cancer

This work aimed at preparing nanomicelles from N-benzyl-N,O-succinyl chitosan (NBSCh) loaded with a curcumin analog, 2,6-bis((3-methoxy-4-hydroxyphenyl) methylene) cyclohexanone, a.k.a. cyqualone (CL), for antineoplastic colon cancer chemotherapy. The CL-loaded NBSCh micelles were spherical and less...

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Detalles Bibliográficos
Autores principales: Sripetthong, Sasikarn, Eze, Fredrick Nwude, Sajomsang, Warayuth, Ovatlarnporn, Chitchamai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10057334/
https://www.ncbi.nlm.nih.gov/pubmed/36985665
http://dx.doi.org/10.3390/molecules28062693