Cargando…

Development of pH-Responsive N-benzyl-N-O-succinyl Chitosan Micelles Loaded with a Curcumin Analog (Cyqualone) for Treatment of Colon Cancer

This work aimed at preparing nanomicelles from N-benzyl-N,O-succinyl chitosan (NBSCh) loaded with a curcumin analog, 2,6-bis((3-methoxy-4-hydroxyphenyl) methylene) cyclohexanone, a.k.a. cyqualone (CL), for antineoplastic colon cancer chemotherapy. The CL-loaded NBSCh micelles were spherical and less...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sripetthong, Sasikarn, Eze, Fredrick Nwude, Sajomsang, Warayuth, Ovatlarnporn, Chitchamai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10057334/ https://www.ncbi.nlm.nih.gov/pubmed/36985665 http://dx.doi.org/10.3390/molecules28062693

Ejemplares similares

Preparation of Self-Assembled, Curcumin-Loaded Nano-Micelles Using Quarternized Chitosan–Vanillin Imine (QCS-Vani Imine) Conjugate and Evaluation of Synergistic Anticancer Effect with Cisplatin
por: Sripetthong, Sasikarn, et al.
Publicado: (2023)

Validated HPLC method for simultaneous quantitative determination of dimethylcurcumin and resveratrol in pluronic-F127 nanomicelles: Formulation with enhanced anticancer efficacy
por: Arakkunakorn, Wasiporn, et al.
Publicado: (2023)

New Insights on Acanthus ebracteatus Vahl: UPLC-ESI-QTOF-MS Profile, Antioxidant, Antimicrobial and Anticancer Activities
por: Olatunji, Opeyemi Joshua, et al.
Publicado: (2022)

Cyclohexanone curcumin analogs inhibit the progression of castration‐resistant prostate cancer in vitro and in vivo
por: Mapoung, Sariya, et al.
Publicado: (2018)

Dehydrozingerone, a Curcumin Analog, as a Potential Anti-Prostate Cancer Inhibitor In Vitro and In Vivo
por: Mapoung, Sariya, et al.
Publicado: (2020)

N-succinyl chitosan–dialdehyde starch hybrid hydrogels for biomedical applications
por: Kamoun, Elbadawy A.
Publicado: (2016)

Chitosan-based self-assembled nanocarriers coordinated to cisplatin for cancer treatment
por: Trummer, Ronny, et al.
Publicado: (2018)

Study on TEMPO-Mediated Oxidation of N-Succinyl Chitosan and the Water Retention Property
por: Li, Aoqi, et al.
Publicado: (2020)

Quaternization of high molecular weight chitosan for increasing intestinal drug absorption using Caco-2 cells as an in vitro intestinal model
por: Wongwanakul, Ratjika, et al.
Publicado: (2023)

Nanogels of Succinylated Glycol Chitosan-Succinyl Prednisolone Conjugate: Preparation, In Vitro Characteristics and Therapeutic Potential
por: Zhou, Haiyan, et al.
Publicado: (2019)

Effects of Paclitaxel-conjugated N-Succinyl-Hydroxyethyl Chitosan Film for Proliferative Cholangitis in Rabbit Biliary Stricture Model
por: Wang, Tao, et al.
Publicado: (2018)

Structural Stabilization of Human Transthyretin by Centella asiatica (L.) Urban Extract: Implications for TTR Amyloidosis
por: Eze, Fredrick Nwude, et al.
Publicado: (2019)

Transthyretin Anti-Amyloidogenic and Fibril Disrupting Activities of Bacopa monnieri (L.) Wettst (Brahmi) Extract
por: Eze, Fredrick Nwude, et al.
Publicado: (2019)

Body mass index and its effects on liver fat content in overweight and obese young adults by proton magnetic resonance spectroscopy technique
por: Pasanta, Duanghathai, et al.
Publicado: (2018)

Nanogels of a Succinylated Glycol Chitosan-Succinyl Prednisolone Conjugate: Release Behavior, Gastrointestinal Distribution, and Systemic Absorption
por: Zhou, Haiyan, et al.
Publicado: (2020)

Altered DNA Binding and Amplification of Human Breast Cancer Suppressor Gene BRCA1 Induced by a Novel Antitumor Compound, [Ru(η(6)-p-phenylethacrynate)Cl(2)(pta)]
por: Chakree, Korawan, et al.
Publicado: (2012)

Succinyl Chitosan-Colistin Conjugates as Promising Drug Delivery Systems
por: Dubashynskaya, Natallia V., et al.
Publicado: (2022)

Releasing N-glycan from Peptide N-terminus by N-terminal Succinylation Assisted Enzymatic Deglycosylation
por: Weng, Yejing, et al.
Publicado: (2015)

pH responsive N-succinyl chitosan/Poly (acrylamide-co-acrylic acid) hydrogels and in vitro release of 5-fluorouracil
por: Bashir, Shahid, et al.
Publicado: (2017)

A Novel pH- and Salt-Responsive N-Succinyl-Chitosan Hydrogel via a One-Step Hydrothermal Process
por: Li, Xingliang, et al.
Publicado: (2019)

Synthesis and characterization of low-toxicity N-caprinoyl-N-trimethyl chitosan as self-assembled micelles carriers for osthole
por: Hu, Xiao-juan, et al.
Publicado: (2013)

Correction: pH responsive N-succinyl chitosan/Poly (acrylamide-co-acrylic acid) hydrogels and in vitro release of 5-fluorouracil
por: Bashir, Shahid, et al.
Publicado: (2017)

N-[4-(N,N,N-Trimethylammonium)Benzyl]Chitosan Chloride as a Gene Carrier: The Influence of Polyplex Composition and Cell Type
por: Raik, Sergei V., et al.
Publicado: (2021)

Chitosan-based intelligent theragnosis nanocomposites enable pH-sensitive drug release with MR-guided imaging for cancer therapy
por: Lim, Eun-Kyung, et al.
Publicado: (2013)

N-Succinyl-chitosan nanoparticles coupled with low-density lipoprotein for targeted osthole-loaded delivery to low-density lipoprotein receptor-rich tumors
por: Zhang, Chun-ge, et al.
Publicado: (2014)

Securidaca inappendiculata Polyphenol Rich Extract Counteracts Cognitive Deficits, Neuropathy, Neuroinflammation and Oxidative Stress in Diabetic Encephalopathic Rats via p38 MAPK/Nrf2/HO-1 Pathways
por: Pang, Xiaojun, et al.
Publicado: (2021)

Antiproliferative Activities of the Lipophilic Fraction of Eucalyptus camaldulensis against MCF-7 Breast Cancer Cells, UPLC-ESI-QTOF-MS Metabolite Profile, and Antioxidative Functions
por: Huang, Yanping, et al.
Publicado: (2022)

Centella asiatica phenolic extract-mediated bio-fabrication of silver nanoparticles: characterization, reduction of industrially relevant dyes in water and antimicrobial activities against foodborne pathogens
por: Eze, Fredrick Nwude, et al.
Publicado: (2019)

Synthesis of biocompatible Konjac glucomannan stabilized silver nanoparticles, with Asystasia gangetica phenolic extract for colorimetric detection of mercury (II) ion
por: Jayeoye, Titilope John, et al.
Publicado: (2022)

N-Benzylisatin
por: Schutte, M., et al.
Publicado: (2012)

N-Benzylaniline
por: Betz, Richard, et al.
Publicado: (2011)

Synthesis and Characterization of Novel Succinyl Chitosan-Dexamethasone Conjugates for Potential Intravitreal Dexamethasone Delivery
por: Dubashynskaya, Natallia V., et al.
Publicado: (2021)

N-Benzyl-N-methylmorpholinium chloride
por: Bian, Yan-Jiang
Publicado: (2008)

N-Benzyl-N-ethylmorpholinium chloride
por: Bian, Yan-Jiang
Publicado: (2008)

Preparation and physicochemical characterization of N-succinyl chitosan-coated liposomes for oral delivery of grape seed extract and evaluation of its effect on pulmonary fibrosis induced by bleomycin in rats
por: Bavarsad, Neda, et al.
Publicado: (2023)

Supramolecular assembly of KAT2A with succinyl-CoA for histone succinylation
por: Wang, Yugang, et al.
Publicado: (2018)

N-Benzyl-2-propynamide
por: Chen, Mei-Mei, et al.
Publicado: (2009)

N-Benzylidenenordehydroabietylamine
por: Rao, Xiao-Ping, et al.
Publicado: (2009)

N-Benzyl Residues as the P1′ Substituents in Phosphorus-Containing Extended Transition State Analog Inhibitors of Metalloaminopeptidases
por: Janiszewska, Kamila, et al.
Publicado: (2020)

Studies on Intermolecular Interaction of N-Glycidyltrimethyl Ammonium Chloride Modified Chitosan/N,N-Dimethyl-N-dodecyl-N-(2,3-epoxy propyl) Ammonium Chloride and Curcumin Delivery
por: Zhang, Cangheng, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_mj1i20mlei5md5m4aj69f82lij