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FOXO3-Activated circFGFBP1 Inhibits Extracellular Matrix Degradation and Nucleus Pulposus Cell Death via miR-9-5p/BMP2 Axis in Intervertebral Disc Degeneration In Vivo and In Vitro

(1) Background: intervertebral disc degeneration (IVDD) defined as the degenerative changes in intervertebral disc is characterized by extracellular matrix (ECM) degradation and death in nucleus pulposus (NP) cells. (2) Methods: The model of IVDD was established in male Sprague Dawley rats using a p...

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Detalles Bibliográficos
Autores principales:	Tan, Yanlin, Wang, Xiaobin, Zhang, Yi, Dai, Zhehao, Li, Jing, Dong, Chuning, Yao, Xingwang, Lu, Chang, Chen, Fei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10057604/ https://www.ncbi.nlm.nih.gov/pubmed/36986573 http://dx.doi.org/10.3390/ph16030473

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