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Surfing the Waves: Differences in Hospitalised COVID-19 Patients across 4 Variant Waves in a Belgian University Hospital
The unprecedented COVID-19 pandemic took the form of successive variant waves, spreading across the globe. We wanted to investigate any shift in hospitalised patients’ profiles throughout the pandemic. For this study, we used a registry that collected data automatically from electronic patient healt...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10057609/ https://www.ncbi.nlm.nih.gov/pubmed/36992327 http://dx.doi.org/10.3390/v15030618 |
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author | Seyler, Lucie Van Nedervelde, Els De Cock, Diederik Mann, Claudia Pien, Karen Allard, Sabine D. Demuyser, Thomas |
author_facet | Seyler, Lucie Van Nedervelde, Els De Cock, Diederik Mann, Claudia Pien, Karen Allard, Sabine D. Demuyser, Thomas |
author_sort | Seyler, Lucie |
collection | PubMed |
description | The unprecedented COVID-19 pandemic took the form of successive variant waves, spreading across the globe. We wanted to investigate any shift in hospitalised patients’ profiles throughout the pandemic. For this study, we used a registry that collected data automatically from electronic patient health records. We compared clinical data and severity scores, using the National Institute of Health (NIH) severity scores, from all patients admitted for COVID-19 during four SARS-CoV-2 variant waves. Our study concluded that patients hospitalised for COVID-19 showed very different profiles across the four variant waves in Belgium. Patients were younger during the Alpha and Delta waves and frailer during the Omicron period. ‘Critical’ patients according to the NIH criteria formed the largest fraction among the Alpha wave patients (47.7%), while ‘severe’ patients formed the largest fraction among Omicron patients (61.6%). We discussed host factors, vaccination status, and other confounders to put this into perspective. High-quality real-life data remain crucial to inform stakeholders and policymakers that shifts in patients’ clinical profiles have an impact on clinical practice. |
format | Online Article Text |
id | pubmed-10057609 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-100576092023-03-30 Surfing the Waves: Differences in Hospitalised COVID-19 Patients across 4 Variant Waves in a Belgian University Hospital Seyler, Lucie Van Nedervelde, Els De Cock, Diederik Mann, Claudia Pien, Karen Allard, Sabine D. Demuyser, Thomas Viruses Article The unprecedented COVID-19 pandemic took the form of successive variant waves, spreading across the globe. We wanted to investigate any shift in hospitalised patients’ profiles throughout the pandemic. For this study, we used a registry that collected data automatically from electronic patient health records. We compared clinical data and severity scores, using the National Institute of Health (NIH) severity scores, from all patients admitted for COVID-19 during four SARS-CoV-2 variant waves. Our study concluded that patients hospitalised for COVID-19 showed very different profiles across the four variant waves in Belgium. Patients were younger during the Alpha and Delta waves and frailer during the Omicron period. ‘Critical’ patients according to the NIH criteria formed the largest fraction among the Alpha wave patients (47.7%), while ‘severe’ patients formed the largest fraction among Omicron patients (61.6%). We discussed host factors, vaccination status, and other confounders to put this into perspective. High-quality real-life data remain crucial to inform stakeholders and policymakers that shifts in patients’ clinical profiles have an impact on clinical practice. MDPI 2023-02-23 /pmc/articles/PMC10057609/ /pubmed/36992327 http://dx.doi.org/10.3390/v15030618 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Seyler, Lucie Van Nedervelde, Els De Cock, Diederik Mann, Claudia Pien, Karen Allard, Sabine D. Demuyser, Thomas Surfing the Waves: Differences in Hospitalised COVID-19 Patients across 4 Variant Waves in a Belgian University Hospital |
title | Surfing the Waves: Differences in Hospitalised COVID-19 Patients across 4 Variant Waves in a Belgian University Hospital |
title_full | Surfing the Waves: Differences in Hospitalised COVID-19 Patients across 4 Variant Waves in a Belgian University Hospital |
title_fullStr | Surfing the Waves: Differences in Hospitalised COVID-19 Patients across 4 Variant Waves in a Belgian University Hospital |
title_full_unstemmed | Surfing the Waves: Differences in Hospitalised COVID-19 Patients across 4 Variant Waves in a Belgian University Hospital |
title_short | Surfing the Waves: Differences in Hospitalised COVID-19 Patients across 4 Variant Waves in a Belgian University Hospital |
title_sort | surfing the waves: differences in hospitalised covid-19 patients across 4 variant waves in a belgian university hospital |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10057609/ https://www.ncbi.nlm.nih.gov/pubmed/36992327 http://dx.doi.org/10.3390/v15030618 |
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