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The Cell Transformation Assay: A Historical Assessment of Current Knowledge of Applications in an Integrated Approach to Testing and Assessment for Non-Genotoxic Carcinogens

The history of the development of the cell transformation assays (CTAs) is described, providing an overview of in vitro cell transformation from its origin to the new transcriptomic-based CTAs. Application of this knowledge is utilized to address how the different types of CTAs, variously addressing...

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Detalles Bibliográficos
Autores principales:	Colacci, Annamaria, Corvi, Raffaella, Ohmori, Kyomi, Paparella, Martin, Serra, Stefania, Da Rocha Carrico, Iris, Vasseur, Paule, Jacobs, Miriam Naomi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10057754/ https://www.ncbi.nlm.nih.gov/pubmed/36982734 http://dx.doi.org/10.3390/ijms24065659

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