Acinetobacter Baumannii Phages: Past, Present and Future

Acinetobacter baumannii (A. baumannii) is one of the most common clinical pathogens and a typical multi-drug resistant (MDR) bacterium. With the increase of drug-resistant A. baumannii infections, it is urgent to find some new treatment strategies, such as phage therapy. In this paper, we described...

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Autores principales: Tu, Qihang, Pu, Mingfang, Li, Yahao, Wang, Yuer, Li, Maochen, Song, Lihua, Li, Mengzhe, An, Xiaoping, Fan, Huahao, Tong, Yigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10057898/
https://www.ncbi.nlm.nih.gov/pubmed/36992382
http://dx.doi.org/10.3390/v15030673
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author Tu, Qihang
Pu, Mingfang
Li, Yahao
Wang, Yuer
Li, Maochen
Song, Lihua
Li, Mengzhe
An, Xiaoping
Fan, Huahao
Tong, Yigang
author_facet Tu, Qihang
Pu, Mingfang
Li, Yahao
Wang, Yuer
Li, Maochen
Song, Lihua
Li, Mengzhe
An, Xiaoping
Fan, Huahao
Tong, Yigang
author_sort Tu, Qihang
collection PubMed
description Acinetobacter baumannii (A. baumannii) is one of the most common clinical pathogens and a typical multi-drug resistant (MDR) bacterium. With the increase of drug-resistant A. baumannii infections, it is urgent to find some new treatment strategies, such as phage therapy. In this paper, we described the different drug resistances of A. baumannii and some basic properties of A. baumannii phages, analyzed the interaction between phages and their hosts, and focused on A. baumannii phage therapies. Finally, we discussed the chance and challenge of phage therapy. This paper aims to provide a more comprehensive understanding of A. baumannii phages and theoretical support for the clinical application of A. baumannii phages.
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spelling pubmed-100578982023-03-30 Acinetobacter Baumannii Phages: Past, Present and Future Tu, Qihang Pu, Mingfang Li, Yahao Wang, Yuer Li, Maochen Song, Lihua Li, Mengzhe An, Xiaoping Fan, Huahao Tong, Yigang Viruses Review Acinetobacter baumannii (A. baumannii) is one of the most common clinical pathogens and a typical multi-drug resistant (MDR) bacterium. With the increase of drug-resistant A. baumannii infections, it is urgent to find some new treatment strategies, such as phage therapy. In this paper, we described the different drug resistances of A. baumannii and some basic properties of A. baumannii phages, analyzed the interaction between phages and their hosts, and focused on A. baumannii phage therapies. Finally, we discussed the chance and challenge of phage therapy. This paper aims to provide a more comprehensive understanding of A. baumannii phages and theoretical support for the clinical application of A. baumannii phages. MDPI 2023-03-03 /pmc/articles/PMC10057898/ /pubmed/36992382 http://dx.doi.org/10.3390/v15030673 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Tu, Qihang
Pu, Mingfang
Li, Yahao
Wang, Yuer
Li, Maochen
Song, Lihua
Li, Mengzhe
An, Xiaoping
Fan, Huahao
Tong, Yigang
Acinetobacter Baumannii Phages: Past, Present and Future
title Acinetobacter Baumannii Phages: Past, Present and Future
title_full Acinetobacter Baumannii Phages: Past, Present and Future
title_fullStr Acinetobacter Baumannii Phages: Past, Present and Future
title_full_unstemmed Acinetobacter Baumannii Phages: Past, Present and Future
title_short Acinetobacter Baumannii Phages: Past, Present and Future
title_sort acinetobacter baumannii phages: past, present and future
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10057898/
https://www.ncbi.nlm.nih.gov/pubmed/36992382
http://dx.doi.org/10.3390/v15030673
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