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DNA Damage Response−Related Proteins Are Prognostic for Outcome in Both Adult and Pediatric Acute Myelogenous Leukemia Patients: Samples from Adults and from Children Enrolled in a Children’s Oncology Group Study

The survival of malignant leukemic cells is dependent on DNA damage repair (DDR) signaling. Reverse Phase Protein Array (RPPA) data sets were assembled using diagnostic samples from 810 adult and 500 pediatric acute myelogenous leukemia (AML) patients and were probed with 412 and 296 strictly valida...

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Detalles Bibliográficos
Autores principales: Hubner, Stefan E., de Camargo Magalhães, Eduardo S., Hoff, Fieke W., Brown, Brandon D., Qiu, Yihua, Horton, Terzah M., Kornblau, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058043/
https://www.ncbi.nlm.nih.gov/pubmed/36982970
http://dx.doi.org/10.3390/ijms24065898