A Bitter Taste Receptor as a Novel Molecular Target on Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma

Cancer-associated fibroblasts (CAFs) execute diverse and complex functions in cancer progression. While reprogramming the crosstalk between CAFs and cancer epithelial cells is a promising avenue to evade the adverse effects of stromal depletion, drugs are limited by their suboptimal pharmacokinetics...

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Detalles Bibliográficos
Autores principales: Hung, Jessica, Perez, Samantha M., Dasa, Siva Sai Krishna, Hall, Sarah P., Heckert, Danielle B., Murphy, Brian P., Crawford, Howard C., Kelly, Kimberly A., Brinton, Lindsey T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058050/
https://www.ncbi.nlm.nih.gov/pubmed/36986488
http://dx.doi.org/10.3390/ph16030389

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