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Resmetirom Ameliorates NASH-Model Mice by Suppressing STAT3 and NF-κB Signaling Pathways in an RGS5-Dependent Manner

Resmetirom, a liver-directed, orally active agonist of THR-β, could play a favorable role in treating NASH, but little is known about the underlying mechanism. A NASH cell model was established to test the preventive effect of resmetirom on this disease in vitro. RNA-seq was used for screening, and...

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Detalles Bibliográficos
Autores principales:	Wang, Xiaojing, Wang, Liangjing, Geng, Lin, Tanaka, Naoki, Ye, Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058113/ https://www.ncbi.nlm.nih.gov/pubmed/36982915 http://dx.doi.org/10.3390/ijms24065843

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