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Hemolysin Co-Regulatory Protein 1 Enhances the Virulence of Clinically Isolated Escherichia coli in KM Mice by Increasing Inflammation and Inducing Pyroptosis
Hemolysin-coregulated protein 1 (Hcp1) is an effector released by the type VI secretion system (T6SS) in certain pathogenic strains of Escherichia coli (E. coli) that causes apoptosis and contributes to the development of meningitis. The exact toxic consequences of Hcp1 and whether it intensifies th...
Autores principales: | Wang, Hao, Lv, Long-Bao, Chen, Li-Ping, Xiao, Jin-Long, Shen, Jue, Gao, Bin, Zhao, Jin-Gang, Han, Dong-Mei, Chen, Bin-Xun, Wang, Shuai, Liu, Gen, Xin, Ai-Guo, Xiao, Peng, Gao, Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058142/ https://www.ncbi.nlm.nih.gov/pubmed/36977062 http://dx.doi.org/10.3390/toxins15030171 |
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