Template Entrance Channel as Possible Allosteric Inhibition and Resistance Site for Quinolines Tricyclic Derivatives in RNA Dependent RNA Polymerase of Bovine Viral Diarrhea Virus

The development of potent non-nucleoside inhibitors (NNIs) could be an alternate strategy to combating infectious bovine viral diarrhea virus (BVDV), other than the traditional vaccination. RNA-dependent RNA polymerase (RdRp) is an essential enzyme for viral replication; therefore, it is one of the...

Descripción completa

Detalles Bibliográficos
Autores principales: Srivastava, Mitul, Mittal, Lovika, Sarmadhikari, Debapriyo, Singh, Vijay Kumar, Fais, Antonella, Kumar, Amit, Asthana, Shailendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058290/
https://www.ncbi.nlm.nih.gov/pubmed/36986476
http://dx.doi.org/10.3390/ph16030376

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058290/
https://www.ncbi.nlm.nih.gov/pubmed/36986476
http://dx.doi.org/10.3390/ph16030376

Ejemplares similares