Cargando…

Comparison of In Vitro Antimelanoma and Antimicrobial Activity of 2,3-Indolo-betulinic Acid and Its Glycine Conjugates

Malignant melanoma is one of the most pressing problems in the developing world. New therapeutic agents that might be effective in treating malignancies that have developed resistance to conventional medications are urgently required. Semisynthesis is an essential method for improving the biological...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lombrea, Adelina, Semenescu, Alexandra-Denisa, Magyari-Pavel, Ioana Zinuca, Turks, Māris, Lugiņina, Jevgeņija, Peipiņš, Uldis, Muntean, Delia, Dehelean, Cristina Adriana, Dinu, Stefania, Danciu, Corina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058300/ https://www.ncbi.nlm.nih.gov/pubmed/36986941 http://dx.doi.org/10.3390/plants12061253

Ejemplares similares

Anticancer Potential of Betulonic Acid Derivatives
por: Lombrea, Adelina, et al.
Publicado: (2021)

Betulin 3,28-di-O-tosylate
por: Peipiņš, Uldis, et al.
Publicado: (2014)

Green Synthesis of Silver Nanoparticles Using Populi gemmae Extract: Preparation, Physicochemical Characterization, Antimicrobial Potential and In Vitro Antiproliferative Assessment
por: Kis, Brigitta, et al.
Publicado: (2022)

The C30-Modulation of Betulinic Acid Using 1,2,4-Triazole: A Promising Strategy for Increasing Its Antimelanoma Cytotoxic Potential
por: Nistor, Gabriela, et al.
Publicado: (2022)

Oxidative Stability and Protective Effect of the Mixture between Helianthus annuus L. and Oenothera biennis L. Oils on 3D Tissue Models of Skin Irritation and Phototoxicity
por: Fecker, Ramona, et al.
Publicado: (2022)

Metal-free glycosylation with glycosyl fluorides in liquid SO(2)
por: Gulbe, Krista, et al.
Publicado: (2021)

Recent Advances Regarding the Phytochemical and Therapeutic Uses of Populus nigra L. Buds
por: Kis, Brigitta, et al.
Publicado: (2020)

A Recent Insight Regarding the Phytochemistry and Bioactivity of Origanum vulgare L. Essential Oil
por: Lombrea, Adelina, et al.
Publicado: (2020)

In Vitro Evaluation of the Antimicrobial Ability and Cytotoxicity on Two Melanoma Cell Lines of a Benzylamide Derivative of Maslinic Acid
por: Pavel, Ioana Zinuca, et al.
Publicado: (2016)

Betulin - a plant-derived cytostatic drug - enhances antitumor immune response
por: Pfarr, Kathrin, et al.
Publicado: (2014)

Sex-Related Differences in Pharmacological Response to CNS Drugs: A Narrative Review
por: Romanescu, Mirabela, et al.
Publicado: (2022)

Synthesis and Immunological Evaluation of Virus-Like Particle-Milbemycin A(3)/A(4) Conjugates
por: Zeltins, Andris, et al.
Publicado: (2017)

Simultaneous and Dose Dependent Melanoma Cytotoxic and Immune Stimulatory Activity of Betulin
por: Pfarr, Kathrin, et al.
Publicado: (2015)

Betulin Complex in γ-Cyclodextrin Derivatives: Properties and Antineoplasic Activities in In Vitro and In Vivo Tumor Models
por: Şoica, Codruta, et al.
Publicado: (2012)

Sex-Related Differences in the Pharmacological Response in SARS-CoV-2 Infection, Dyslipidemia, and Diabetes Mellitus: A Narrative Review
por: Lombrea, Adelina, et al.
Publicado: (2023)

Current State of Knowledge Regarding WHO Critical Priority Pathogens: Mechanisms of Resistance and Proposed Solutions through Candidates Such as Essential Oils
por: Badescu, Bianca, et al.
Publicado: (2022)

Phytochemical Characterization and Biological Evaluation of Origanum vulgare L. Essential Oil Formulated as Polymeric Micelles Drug Delivery Systems
por: Bora, Larisa, et al.
Publicado: (2022)

Biological Evaluation of Black Chokeberry Extract Free and Embedded in Two Mesoporous Silica-Type Matrices
por: Buda, Valentina, et al.
Publicado: (2020)

Novel Triterpenic Acid—Benzotriazole Esters Act as Pro-Apoptotic Antimelanoma Agents
por: Mioc, Marius, et al.
Publicado: (2022)

Phytochemical and Biological Screening of Oenothera biennis L. Hydroalcoholic Extract
por: Fecker, Ramona, et al.
Publicado: (2020)

The Anti-Melanoma Effect of Betulinic Acid Functionalized Gold Nanoparticles: A Mechanistic In Vitro Approach
por: Ghiulai, Roxana, et al.
Publicado: (2022)

Assessment of the Antiangiogenic and Anti-Inflammatory Properties of a Maslinic Acid Derivative and its Potentiation using Zinc Chloride
por: Pavel, Ioana Zinuca, et al.
Publicado: (2019)

An Up-To-Date Review Regarding Cutaneous Benefits of Origanum vulgare L. Essential Oil
por: Bora, Larisa, et al.
Publicado: (2022)

The Cytotoxic Effects of Betulin-Conjugated Gold Nanoparticles as Stable Formulations in Normal and Melanoma Cells
por: Mioc, Marius, et al.
Publicado: (2018)

Antimelanoma and Antityrosinase from Alpinia galangal Constituents
por: Lo, Chih-Yu, et al.
Publicado: (2013)

Antimelanoma activities of chimeric thiazole–androstenone derivatives
por: Chambers, Steven A., et al.
Publicado: (2021)

Carotenoids from Marine Microalgae as Antimelanoma Agents
por: Ferraz, Christiane Adrielly Alves, et al.
Publicado: (2022)

In Vitro Antimelanoma Properties of Verbena officinalis Fractions
por: Nisar, Rabia, et al.
Publicado: (2022)

Cocrystal Formation of Betulinic Acid and Ascorbic Acid: Synthesis, Physico-Chemical Assessment, Antioxidant, and Antiproliferative Activity
por: Nicolov, Mirela, et al.
Publicado: (2019)

Cutaneous Polymeric-Micelles-Based Hydrogel Containing Origanum vulgare L. Essential Oil: In Vitro Release and Permeation, Angiogenesis, and Safety Profile In Ovo
por: Avram, Ștefana, et al.
Publicado: (2023)

Crystal structure of 3-deoxy-3-nitromethyl-1,2;5,6-di-O-isopropylidene-α-d-allofuranose
por: Lugiņina, Jevgeņija, et al.
Publicado: (2016)

An In Vitro-In Vivo Evaluation of the Antiproliferative and Antiangiogenic Effect of Flavone Apigenin against SK-MEL-24 Human Melanoma Cell Line
por: Ghiƫu, Alexandra, et al.
Publicado: (2021)

Betulinic Acid in Complex with a Gamma-Cyclodextrin Derivative Decreases Proliferation and in Vivo Tumor Development of Non-Metastatic and Metastatic B164A5 Cells
por: Soica, Codruta, et al.
Publicado: (2014)

Dacarbazine mediates antimelanoma effects via NK cells
por: Hervieu, Alice, et al.
Publicado: (2013)

PUMA: a puzzle piece in chloroquine’s antimelanoma activity
por: Amaravadi, Ravi K.
Publicado: (2013)

Current State of Knowledge Regarding WHO High Priority Pathogens—Resistance Mechanisms and Proposed Solutions through Candidates Such as Essential Oils: A Systematic Review
por: Romanescu, Mirabela, et al.
Publicado: (2023)

Assessment of Betulinic Acid Cytotoxicity and Mitochondrial Metabolism Impairment in a Human Melanoma Cell Line
por: Coricovac, Dorina, et al.
Publicado: (2021)

Integrin Targeting Enhances the Antimelanoma Effect of Annexin V in Mice
por: Zhu, Jingyi, et al.
Publicado: (2023)

The Antimelanoma Biological Assessment of Triterpenic Acid Functionalized Gold Nanoparticles
por: Mioc, Marius, et al.
Publicado: (2023)

Inorganic Element Determination of Romanian Populus nigra L. Buds Extract and In Vitro Antiproliferative and Pro-Apoptotic Evaluation on A549 Human Lung Cancer Cell Line
por: Kis, Brigitta, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_jssug6574efbqld4ra1dpa0mtu