Cargando…
A Therapeutic Vaccine Targeting Rat BORIS (CTCFL) for the Treatment of Rat Breast Cancer Tumors
Cancer testis antigens are ideal for tumor immunotherapy due to their testis-restricted expression. We previously showed that an immunotherapeutic vaccine targeting the germ cell-specific transcription factor BORIS (CTCFL) was highly effective in treating aggressive breast cancer in the 4T1 mouse mo...
Autores principales: | Loukinov, Dmitri, Anderson, Amanda Laust, Mkrtichyan, Mikayel, Ghochikyan, Anahit, Rivero-Hinojosa, Samuel, Tucker, Jo, Lobanenkov, Victor, Agadjanyan, Michael G., Nelson, Edward L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058450/ https://www.ncbi.nlm.nih.gov/pubmed/36983050 http://dx.doi.org/10.3390/ijms24065976 |
Ejemplares similares
-
Expression of the Epigenetic factor BORIS (CTCFL) in the Human Genome
por: de Necochea-Campion, Rosalia, et al.
Publicado: (2011) -
BORIS/CTCFL-mediated transcriptional regulation of the hTERT telomerase gene in testicular and ovarian tumor cells
por: Renaud, Stéphanie, et al.
Publicado: (2011) -
The downregulation of putative anticancer target BORIS/CTCFL in an addicted myeloid cancer cell line modulates the expression of multiple protein coding and ncRNA genes
por: Teplyakov, Evgeny, et al.
Publicado: (2017) -
The combined action of CTCF and its testis-specific paralog BORIS is essential for spermatogenesis
por: Rivero-Hinojosa, Samuel, et al.
Publicado: (2021) -
The cancer-associated CTCFL/BORIS protein targets multiple classes of genomic repeats, with a distinct binding and functional preference for humanoid-specific SVA transposable elements
por: Pugacheva, Elena M., et al.
Publicado: (2016)