Safety and Immunogenicity of Recombinant Bacille Calmette-Guérin Strain VPM1002 and Its Derivatives in a Goat Model

A more effective vaccine against tuberculosis than Bacille Calmette-Guérin (BCG) is urgently needed. BCG derived recombinant VPM1002 has been found to be more efficacious and safer than the parental strain in mice models. Newer candidates, such as VPM1002 Δpdx1 (PDX) and VPM1002 ΔnuoG (NUOG), were g...

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Detalles Bibliográficos
Autores principales: Figl, Julia, Köhler, Heike, Wedlich, Nadine, Liebler-Tenorio, Elisabeth M., Grode, Leander, Parzmair, Gerald, Krishnamoorthy, Gopinath, Nieuwenhuizen, Natalie E., Kaufmann, Stefan H. E., Menge, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058566/
https://www.ncbi.nlm.nih.gov/pubmed/36982586
http://dx.doi.org/10.3390/ijms24065509

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