Properties of Poly (Lactic-co-Glycolic Acid) and Progress of Poly (Lactic-co-Glycolic Acid)-Based Biodegradable Materials in Biomedical Research

In recent years, biodegradable polymers have gained the attention of many researchers for their promising applications, especially in drug delivery, due to their good biocompatibility and designable degradation time. Poly (lactic-co-glycolic acid) (PLGA) is a biodegradable functional polymer made fr...

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Detalles Bibliográficos
Autores principales: Lu, Yue, Cheng, Dongfang, Niu, Baohua, Wang, Xiuzhi, Wu, Xiaxia, Wang, Aiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058621/
https://www.ncbi.nlm.nih.gov/pubmed/36986553
http://dx.doi.org/10.3390/ph16030454
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author Lu, Yue
Cheng, Dongfang
Niu, Baohua
Wang, Xiuzhi
Wu, Xiaxia
Wang, Aiping
author_facet Lu, Yue
Cheng, Dongfang
Niu, Baohua
Wang, Xiuzhi
Wu, Xiaxia
Wang, Aiping
author_sort Lu, Yue
collection PubMed
description In recent years, biodegradable polymers have gained the attention of many researchers for their promising applications, especially in drug delivery, due to their good biocompatibility and designable degradation time. Poly (lactic-co-glycolic acid) (PLGA) is a biodegradable functional polymer made from the polymerization of lactic acid (LA) and glycolic acid (GA) and is widely used in pharmaceuticals and medical engineering materials because of its biocompatibility, non-toxicity, and good plasticity. The aim of this review is to illustrate the progress of research on PLGA in biomedical applications, as well as its shortcomings, to provide some assistance for its future research development.
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spelling pubmed-100586212023-03-30 Properties of Poly (Lactic-co-Glycolic Acid) and Progress of Poly (Lactic-co-Glycolic Acid)-Based Biodegradable Materials in Biomedical Research Lu, Yue Cheng, Dongfang Niu, Baohua Wang, Xiuzhi Wu, Xiaxia Wang, Aiping Pharmaceuticals (Basel) Review In recent years, biodegradable polymers have gained the attention of many researchers for their promising applications, especially in drug delivery, due to their good biocompatibility and designable degradation time. Poly (lactic-co-glycolic acid) (PLGA) is a biodegradable functional polymer made from the polymerization of lactic acid (LA) and glycolic acid (GA) and is widely used in pharmaceuticals and medical engineering materials because of its biocompatibility, non-toxicity, and good plasticity. The aim of this review is to illustrate the progress of research on PLGA in biomedical applications, as well as its shortcomings, to provide some assistance for its future research development. MDPI 2023-03-17 /pmc/articles/PMC10058621/ /pubmed/36986553 http://dx.doi.org/10.3390/ph16030454 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Lu, Yue
Cheng, Dongfang
Niu, Baohua
Wang, Xiuzhi
Wu, Xiaxia
Wang, Aiping
Properties of Poly (Lactic-co-Glycolic Acid) and Progress of Poly (Lactic-co-Glycolic Acid)-Based Biodegradable Materials in Biomedical Research
title Properties of Poly (Lactic-co-Glycolic Acid) and Progress of Poly (Lactic-co-Glycolic Acid)-Based Biodegradable Materials in Biomedical Research
title_full Properties of Poly (Lactic-co-Glycolic Acid) and Progress of Poly (Lactic-co-Glycolic Acid)-Based Biodegradable Materials in Biomedical Research
title_fullStr Properties of Poly (Lactic-co-Glycolic Acid) and Progress of Poly (Lactic-co-Glycolic Acid)-Based Biodegradable Materials in Biomedical Research
title_full_unstemmed Properties of Poly (Lactic-co-Glycolic Acid) and Progress of Poly (Lactic-co-Glycolic Acid)-Based Biodegradable Materials in Biomedical Research
title_short Properties of Poly (Lactic-co-Glycolic Acid) and Progress of Poly (Lactic-co-Glycolic Acid)-Based Biodegradable Materials in Biomedical Research
title_sort properties of poly (lactic-co-glycolic acid) and progress of poly (lactic-co-glycolic acid)-based biodegradable materials in biomedical research
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058621/
https://www.ncbi.nlm.nih.gov/pubmed/36986553
http://dx.doi.org/10.3390/ph16030454
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