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Metabolic Features of Increased Gut Permeability, Inflammation, and Altered Energy Metabolism Distinguish Agricultural Workers at Risk for Mesoamerican Nephropathy

Mesoamerican nephropathy (MeN) is a form of chronic kidney disease found predominantly in young men in Mesoamerica. Strenuous agricultural labor is a consistent risk factor for MeN, but the pathophysiologic mechanism leading to disease is poorly understood. We compared the urine metabolome among men...

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Detalles Bibliográficos
Autores principales: Raines, Nathan H., Leone, Dominick A., O’Callaghan-Gordo, Cristina, Ramirez-Rubio, Oriana, Amador, Juan José, Lopez Pilarte, Damaris, Delgado, Iris S., Leibler, Jessica H., Embade, Nieves, Gil-Redondo, Rubén, Bruzzone, Chiara, Bizkarguenaga, Maider, Scammell, Madeleine K., Parikh, Samir M., Millet, Oscar, Brooks, Daniel R., Friedman, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058628/
https://www.ncbi.nlm.nih.gov/pubmed/36984765
http://dx.doi.org/10.3390/metabo13030325