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Multifunctional Layered Double Hydroxides for Drug Delivery and Imaging

Two-dimensional nanomaterials, particularly layered double hydroxides (LDHs), have been widely applied in the biomedical field owing to their biocompatibility, biodegradability, controllable drug release/loading ability, and enhanced cellular permeability. Since the first study analyzing intercalati...

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Detalles Bibliográficos
Autores principales: Yu, Seungjin, Choi, Goeun, Choy, Jin-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058705/
https://www.ncbi.nlm.nih.gov/pubmed/36985996
http://dx.doi.org/10.3390/nano13061102
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author Yu, Seungjin
Choi, Goeun
Choy, Jin-Ho
author_facet Yu, Seungjin
Choi, Goeun
Choy, Jin-Ho
author_sort Yu, Seungjin
collection PubMed
description Two-dimensional nanomaterials, particularly layered double hydroxides (LDHs), have been widely applied in the biomedical field owing to their biocompatibility, biodegradability, controllable drug release/loading ability, and enhanced cellular permeability. Since the first study analyzing intercalative LDHs in 1999, numerous studies have investigated their biomedical applications, including drug delivery and imaging; recent research has focused on the design and development of multifunctional LDHs. This review summarizes the synthetic strategies and in-vivo and in-vitro therapeutic actions and targeting properties of single-function LDH-based nanohybrids and recently reported (from 2019 to 2023) multifunctional systems developed for drug delivery and/or bio-imaging.
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spelling pubmed-100587052023-03-30 Multifunctional Layered Double Hydroxides for Drug Delivery and Imaging Yu, Seungjin Choi, Goeun Choy, Jin-Ho Nanomaterials (Basel) Review Two-dimensional nanomaterials, particularly layered double hydroxides (LDHs), have been widely applied in the biomedical field owing to their biocompatibility, biodegradability, controllable drug release/loading ability, and enhanced cellular permeability. Since the first study analyzing intercalative LDHs in 1999, numerous studies have investigated their biomedical applications, including drug delivery and imaging; recent research has focused on the design and development of multifunctional LDHs. This review summarizes the synthetic strategies and in-vivo and in-vitro therapeutic actions and targeting properties of single-function LDH-based nanohybrids and recently reported (from 2019 to 2023) multifunctional systems developed for drug delivery and/or bio-imaging. MDPI 2023-03-19 /pmc/articles/PMC10058705/ /pubmed/36985996 http://dx.doi.org/10.3390/nano13061102 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Yu, Seungjin
Choi, Goeun
Choy, Jin-Ho
Multifunctional Layered Double Hydroxides for Drug Delivery and Imaging
title Multifunctional Layered Double Hydroxides for Drug Delivery and Imaging
title_full Multifunctional Layered Double Hydroxides for Drug Delivery and Imaging
title_fullStr Multifunctional Layered Double Hydroxides for Drug Delivery and Imaging
title_full_unstemmed Multifunctional Layered Double Hydroxides for Drug Delivery and Imaging
title_short Multifunctional Layered Double Hydroxides for Drug Delivery and Imaging
title_sort multifunctional layered double hydroxides for drug delivery and imaging
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058705/
https://www.ncbi.nlm.nih.gov/pubmed/36985996
http://dx.doi.org/10.3390/nano13061102
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