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Multifunctional Layered Double Hydroxides for Drug Delivery and Imaging
Two-dimensional nanomaterials, particularly layered double hydroxides (LDHs), have been widely applied in the biomedical field owing to their biocompatibility, biodegradability, controllable drug release/loading ability, and enhanced cellular permeability. Since the first study analyzing intercalati...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058705/ https://www.ncbi.nlm.nih.gov/pubmed/36985996 http://dx.doi.org/10.3390/nano13061102 |
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author | Yu, Seungjin Choi, Goeun Choy, Jin-Ho |
author_facet | Yu, Seungjin Choi, Goeun Choy, Jin-Ho |
author_sort | Yu, Seungjin |
collection | PubMed |
description | Two-dimensional nanomaterials, particularly layered double hydroxides (LDHs), have been widely applied in the biomedical field owing to their biocompatibility, biodegradability, controllable drug release/loading ability, and enhanced cellular permeability. Since the first study analyzing intercalative LDHs in 1999, numerous studies have investigated their biomedical applications, including drug delivery and imaging; recent research has focused on the design and development of multifunctional LDHs. This review summarizes the synthetic strategies and in-vivo and in-vitro therapeutic actions and targeting properties of single-function LDH-based nanohybrids and recently reported (from 2019 to 2023) multifunctional systems developed for drug delivery and/or bio-imaging. |
format | Online Article Text |
id | pubmed-10058705 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-100587052023-03-30 Multifunctional Layered Double Hydroxides for Drug Delivery and Imaging Yu, Seungjin Choi, Goeun Choy, Jin-Ho Nanomaterials (Basel) Review Two-dimensional nanomaterials, particularly layered double hydroxides (LDHs), have been widely applied in the biomedical field owing to their biocompatibility, biodegradability, controllable drug release/loading ability, and enhanced cellular permeability. Since the first study analyzing intercalative LDHs in 1999, numerous studies have investigated their biomedical applications, including drug delivery and imaging; recent research has focused on the design and development of multifunctional LDHs. This review summarizes the synthetic strategies and in-vivo and in-vitro therapeutic actions and targeting properties of single-function LDH-based nanohybrids and recently reported (from 2019 to 2023) multifunctional systems developed for drug delivery and/or bio-imaging. MDPI 2023-03-19 /pmc/articles/PMC10058705/ /pubmed/36985996 http://dx.doi.org/10.3390/nano13061102 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Yu, Seungjin Choi, Goeun Choy, Jin-Ho Multifunctional Layered Double Hydroxides for Drug Delivery and Imaging |
title | Multifunctional Layered Double Hydroxides for Drug Delivery and Imaging |
title_full | Multifunctional Layered Double Hydroxides for Drug Delivery and Imaging |
title_fullStr | Multifunctional Layered Double Hydroxides for Drug Delivery and Imaging |
title_full_unstemmed | Multifunctional Layered Double Hydroxides for Drug Delivery and Imaging |
title_short | Multifunctional Layered Double Hydroxides for Drug Delivery and Imaging |
title_sort | multifunctional layered double hydroxides for drug delivery and imaging |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058705/ https://www.ncbi.nlm.nih.gov/pubmed/36985996 http://dx.doi.org/10.3390/nano13061102 |
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