Cargando…

Development of National Antimicrobial Intravenous-to-Oral Switch Criteria and Decision Aid

Introduction: Antimicrobial stewardship (AMS) strategies, such as intravenous-to-oral switch (IVOS), promote optimal antimicrobial use, contributing to safer and more effective patient care and tackling antimicrobial resistance (AMR). Aim: This study aimed to achieve nationwide multidisciplinary exp...

Descripción completa

Detalles Bibliográficos
Autores principales: Harvey, Eleanor J., Hand, Kieran, Weston, Dale, Ashiru-Oredope, Diane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058706/
https://www.ncbi.nlm.nih.gov/pubmed/36983089
http://dx.doi.org/10.3390/jcm12062086
_version_ 1785016698185711616
author Harvey, Eleanor J.
Hand, Kieran
Weston, Dale
Ashiru-Oredope, Diane
author_facet Harvey, Eleanor J.
Hand, Kieran
Weston, Dale
Ashiru-Oredope, Diane
author_sort Harvey, Eleanor J.
collection PubMed
description Introduction: Antimicrobial stewardship (AMS) strategies, such as intravenous-to-oral switch (IVOS), promote optimal antimicrobial use, contributing to safer and more effective patient care and tackling antimicrobial resistance (AMR). Aim: This study aimed to achieve nationwide multidisciplinary expert consensus on antimicrobial IVOS criteria for timely switch in hospitalised adult patients and to design an IVOS decision aid to operationalise agreed IVOS criteria in the hospital setting. Method: A four-step Delphi process was chosen to achieve expert consensus on IVOS criteria and decision aid; it included (Step One) Pilot/1st round questionnaire, (Step Two) Virtual meeting, (Step Three) 2nd round questionnaire and (Step 4) Workshop. This study follows the Appraisal of Guidelines for Research and Evaluation II instrument checklist. Results: The Step One questionnaire of 42 IVOS criteria had 24 respondents, 15 of whom participated in Step Two, in which 37 criteria were accepted for the next step. Step Three had 242 respondents (England n = 195, Northern Ireland n = 18, Scotland n = 18, Wales n = 11); 27 criteria were accepted. Step Four had 48 survey respondents and 33 workshop participants; consensus was achieved for 24 criteria and comments were received on a proposed IVOS decision aid. Research recommendations include the use of evidence-based standardised IVOS criteria. Discussion and Conclusion: This study achieved nationwide expert consensus on antimicrobial IVOS criteria for timely switch in the hospitalised adult population. For criteria operationalisation, an IVOS decision aid was developed. Further research is required to provide clinical validation of the consensus IVOS criteria and to expand this work into the paediatric and international settings.
format Online
Article
Text
id pubmed-10058706
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-100587062023-03-30 Development of National Antimicrobial Intravenous-to-Oral Switch Criteria and Decision Aid Harvey, Eleanor J. Hand, Kieran Weston, Dale Ashiru-Oredope, Diane J Clin Med Article Introduction: Antimicrobial stewardship (AMS) strategies, such as intravenous-to-oral switch (IVOS), promote optimal antimicrobial use, contributing to safer and more effective patient care and tackling antimicrobial resistance (AMR). Aim: This study aimed to achieve nationwide multidisciplinary expert consensus on antimicrobial IVOS criteria for timely switch in hospitalised adult patients and to design an IVOS decision aid to operationalise agreed IVOS criteria in the hospital setting. Method: A four-step Delphi process was chosen to achieve expert consensus on IVOS criteria and decision aid; it included (Step One) Pilot/1st round questionnaire, (Step Two) Virtual meeting, (Step Three) 2nd round questionnaire and (Step 4) Workshop. This study follows the Appraisal of Guidelines for Research and Evaluation II instrument checklist. Results: The Step One questionnaire of 42 IVOS criteria had 24 respondents, 15 of whom participated in Step Two, in which 37 criteria were accepted for the next step. Step Three had 242 respondents (England n = 195, Northern Ireland n = 18, Scotland n = 18, Wales n = 11); 27 criteria were accepted. Step Four had 48 survey respondents and 33 workshop participants; consensus was achieved for 24 criteria and comments were received on a proposed IVOS decision aid. Research recommendations include the use of evidence-based standardised IVOS criteria. Discussion and Conclusion: This study achieved nationwide expert consensus on antimicrobial IVOS criteria for timely switch in the hospitalised adult population. For criteria operationalisation, an IVOS decision aid was developed. Further research is required to provide clinical validation of the consensus IVOS criteria and to expand this work into the paediatric and international settings. MDPI 2023-03-07 /pmc/articles/PMC10058706/ /pubmed/36983089 http://dx.doi.org/10.3390/jcm12062086 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Harvey, Eleanor J.
Hand, Kieran
Weston, Dale
Ashiru-Oredope, Diane
Development of National Antimicrobial Intravenous-to-Oral Switch Criteria and Decision Aid
title Development of National Antimicrobial Intravenous-to-Oral Switch Criteria and Decision Aid
title_full Development of National Antimicrobial Intravenous-to-Oral Switch Criteria and Decision Aid
title_fullStr Development of National Antimicrobial Intravenous-to-Oral Switch Criteria and Decision Aid
title_full_unstemmed Development of National Antimicrobial Intravenous-to-Oral Switch Criteria and Decision Aid
title_short Development of National Antimicrobial Intravenous-to-Oral Switch Criteria and Decision Aid
title_sort development of national antimicrobial intravenous-to-oral switch criteria and decision aid
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058706/
https://www.ncbi.nlm.nih.gov/pubmed/36983089
http://dx.doi.org/10.3390/jcm12062086
work_keys_str_mv AT harveyeleanorj developmentofnationalantimicrobialintravenoustooralswitchcriteriaanddecisionaid
AT handkieran developmentofnationalantimicrobialintravenoustooralswitchcriteriaanddecisionaid
AT westondale developmentofnationalantimicrobialintravenoustooralswitchcriteriaanddecisionaid
AT ashiruoredopediane developmentofnationalantimicrobialintravenoustooralswitchcriteriaanddecisionaid