Cargando…

Physiologically Based Pharmacokinetic Modelling to Predict Pharmacokinetics of Enavogliflozin, a Sodium-Dependent Glucose Transporter 2 Inhibitor, in Humans

Enavogliflozin is a sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor approved for clinical use in South Korea. As SGLT2 inhibitors are a treatment option for patients with diabetes, enavogliflozin is expected to be prescribed in various populations. Physiologically based pharmacokinetic (P...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Min-Soo, Song, Yoo-Kyung, Choi, Ji-Soo, Ji, Hye Young, Yang, Eunsuk, Park, Joon Seok, Kim, Hyung Sik, Kim, Min-Joo, Cho, In-Kyung, Chung, Suk-Jae, Chae, Yoon-Jee, Lee, Kyeong-Ryoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058973/ https://www.ncbi.nlm.nih.gov/pubmed/36986803 http://dx.doi.org/10.3390/pharmaceutics15030942

Ejemplares similares

Pharmacokinetics and Tissue Distribution of Enavogliflozin in Mice and Rats
por: Pang, Minyeong, et al.
Publicado: (2022)

Development of Physiologically Based Pharmacokinetic Model for Orally Administered Fexuprazan in Humans
por: Jeong, Yoo-Seong, et al.
Publicado: (2021)

Pharmacokinetic Characterization of Supinoxin and Its Physiologically Based Pharmacokinetic Modeling in Rats
por: Song, Yoo-Kyung, et al.
Publicado: (2021)

Pharmacokinetic Estimation Models-based Approach to Predict Clinical Implications for CYP Induction by Calcitriol in Human Cryopreserved Hepatocytes and HepaRG Cells
por: Chae, Yoon-Jee, et al.
Publicado: (2021)

Prediction of Pharmacokinetics of IDP-73152 in Humans Using Physiologically-Based Pharmacokinetics
por: Lee, Myongjae, et al.
Publicado: (2022)

In Vivo Toxicity and Pharmacokinetics of Polytetrafluoroethylene Microplastics in ICR Mice
por: Lee, Sijoon, et al.
Publicado: (2022)

Application of physiologically based pharmacokinetic modeling in predicting drug–drug interactions for sarpogrelate hydrochloride in humans
por: Min, Jee Sun, et al.
Publicado: (2016)

Bioanalysis of niclosamide in plasma using liquid chromatography-tandem mass and application to pharmacokinetics in rats and dogs
por: Choi, Hae-In, et al.
Publicado: (2021)

Analysis of Time-Dependent Pharmacokinetics Using In Vitro–In Vivo Extrapolation and Physiologically Based Pharmacokinetic Modeling
por: Kim, Min-Chang, et al.
Publicado: (2022)

Quercetin Is a Flavonoid Breast Cancer Resistance Protein Inhibitor with an Impact on the Oral Pharmacokinetics of Sulfasalazine in Rats
por: Song, Yoo-Kyung, et al.
Publicado: (2020)

Population Pharmacokinetic Method to Predict Within-Subject Variability Using Single-Period Clinical Data
por: Kang, Won-ho, et al.
Publicado: (2021)

Population Pharmacokinetics of Primaquine in the Korean Population
por: Lee, Woo-Yul, et al.
Publicado: (2021)

Integration of a Physiologically Based Pharmacokinetic and Pharmacodynamic Model for Tegoprazan and Its Metabolite: Application for Predicting Food Effect and Intragastric pH Alterations
por: Jeong, Hyeon-Cheol, et al.
Publicado: (2022)

Model-Based Prediction of Acid Suppression and Proposal of a New Dosing Regimen of Fexuprazan in Humans
por: Kim, Min-Soo, et al.
Publicado: (2022)

Clinical Pharmacokinetics of Approved RNA Therapeutics
por: Jo, Seong Jun, et al.
Publicado: (2023)

A Population Pharmacokinetic Model of Intravenous Dexmedetomidine for Mechanically Ventilated Children after Neurosurgery
por: Song, In-Kyung, et al.
Publicado: (2019)

Efficacy and Safety of Enavogliflozin versus Dapagliflozin as Add-on to Metformin in Patients with Type 2 Diabetes Mellitus: A 24-Week, Double-Blind, Randomized Trial
por: Han, Kyung Ah, et al.
Publicado: (2023)

Comparative Pharmacokinetics and Pharmacodynamics of a Novel Sodium-Glucose Cotransporter 2 Inhibitor, DWP16001, with Dapagliflozin and Ipragliflozin
por: Choi, Min-Koo, et al.
Publicado: (2020)

Benzisothiazolinone: Pharmacokinetics, Tissue Distribution, and Mass Balance Studies in Rats
por: Jo, Seong Jun, et al.
Publicado: (2023)

Polymer micelle formulation for the proteasome inhibitor drug carfilzomib: Anticancer efficacy and pharmacokinetic studies in mice
por: Park, Ji Eun, et al.
Publicado: (2017)

Physiologically based pharmacokinetic modelling of atomoxetine with regard to CYP2D6 genotypes
por: Kim, Se-Hyung, et al.
Publicado: (2018)

Effects of amoxicillin/clavulanic acid on the pharmacokinetics of valproic acid
por: Lee, Soo-Yun, et al.
Publicado: (2015)

Pharmacokinetics of Glutathione and Its Metabolites in Normal Subjects
por: Hong, Sae-Yong, et al.
Publicado: (2005)

A pharmacokinetic comparison of two voriconazole formulations and the effect of CYP2C19 polymorphism on their pharmacokinetic profiles
por: Chung, Hyewon, et al.
Publicado: (2015)

Application of Minimal Physiologically-Based Pharmacokinetic Model to Simulate Lung and Trachea Exposure of Pyronaridine and Artesunate in Hamsters
por: Kang, Dong Wook, et al.
Publicado: (2023)

Navigating the Future of Diabetes Treatment with New Drugs: Focusing on the Possibilities and Prospects of Enavogliflozin
por: Rhee, Sang Youl
Publicado: (2023)

The safety, pharmacodynamics, and pharmacokinetics of immediate-release formulation containing esomeprazole 20 mg/sodium bicarbonate 800 mg in healthy adult male
por: Kim, Dasohm, et al.
Publicado: (2019)

Effects of cytochrome P450 oxidoreductase genotypes on the pharmacokinetics of amlodipine in healthy Korean subjects
por: Han, Ji Min, et al.
Publicado: (2020)

US-localized diffuse optical tomography in breast cancer: comparison with pharmacokinetic parameters of DCE-MRI and with pathologic biomarkers
por: Kim, Min Jung, et al.
Publicado: (2016)

Pharmacokinetic Properties of Acetyl Tributyl Citrate, a Pharmaceutical Excipient
por: Kim, Hyeon, et al.
Publicado: (2018)

Comparison of pharmacokinetic characteristics of sildenafil citrate chewable tablets and film-coated tablets in healthy male subjects
por: Yoo, Hyounggyoon, et al.
Publicado: (2017)

Pharmacokinetics of Tyrosol Metabolites in Rats
por: Lee, Da-Hye, et al.
Publicado: (2016)

Effects of dexamethasone coadministered with oseltamivir on the pharmacokinetics of oseltamivir in healthy volunteers
por: Jang, Kyungho, et al.
Publicado: (2017)

Pharmacokinetic Evaluation of Metabolic Drug Interactions between Repaglinide and Celecoxib by a Bioanalytical HPLC Method for Their Simultaneous Determination with Fluorescence Detection
por: Han, Dong-Gyun, et al.
Publicado: (2019)

Pharmacokinetics and Monte Carlo Simulation of Meropenem in Critically Ill Adult Patients Receiving Extracorporeal Membrane Oxygenation
por: Lee, Jae Ha, et al.
Publicado: (2021)

Pharmacokinetic analysis of new synthetic antimalarial N-251
por: Okada, Kazuaki, et al.
Publicado: (2019)

Pharmacokinetic Characterization of LW6, a Novel Hypoxia-Inducible Factor-1α (HIF-1α) Inhibitor in Mice
por: Lee, Ji-Yoon, et al.
Publicado: (2021)

Species Differences in Stereoselective Pharmacokinetics of HSG4112, A New Anti-Obesity Agent
por: Bae, In Yong, et al.
Publicado: (2020)

A Machine Learning-Based Identification of Genes Affecting the Pharmacokinetics of Tacrolimus Using the DMET(TM) Plus Platform
por: Gim, Jeong-An, et al.
Publicado: (2020)

External Validation of a Pharmacokinetic Model of Propofol for Target-Controlled Infusion in Children under Two Years Old
por: Ji, Sang-Hwan, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_t4b1khouj4mlf757mgep8750q0