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Mucormycosis in a Patient with Severe COVID-19 Disease—The First Case Report in Romania and a Literature Review
Introduction: COVID-19 infection is often associated with a vast spectrum of opportunistic bacterial and fungal infections. Herein, we share a summary of the first case of COVID-19-associated mucormycosis (CAM) in a patient from Romania. Case presentation: A 51-year-old male non-smoker, with no know...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058997/ https://www.ncbi.nlm.nih.gov/pubmed/36984555 http://dx.doi.org/10.3390/medicina59030555 |
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author | Mahler, Beatrice Parliteanu, Oana Andreea Alexe, Octavian Rîșcă Popazu, Corina Ene, Catalina Elena Timar, Bogdan Constantinescu, Tudor |
author_facet | Mahler, Beatrice Parliteanu, Oana Andreea Alexe, Octavian Rîșcă Popazu, Corina Ene, Catalina Elena Timar, Bogdan Constantinescu, Tudor |
author_sort | Mahler, Beatrice |
collection | PubMed |
description | Introduction: COVID-19 infection is often associated with a vast spectrum of opportunistic bacterial and fungal infections. Herein, we share a summary of the first case of COVID-19-associated mucormycosis (CAM) in a patient from Romania. Case presentation: A 51-year-old male non-smoker, with no known relevant medical history, who denied any previous alcohol use and was vaccinated against COVID-19 (complete scheme with Vaxzevria), was admitted to the hospital for severe COVID-19 infection. The first mucormycosis-related symptoms were reported on the eighth day of admission and were followed by the rapid deterioration of the patient’s condition and, consequently, death. The main aggravating factors, which were identified to be associated with the development of mucormycosis and with the poor outcome, were the association of severe COVID-19, new-onset COVID-19-triggered type 2 diabetes, and corticoid treatment for severe COVID-19. Conclusion: The association between severe COVID-19 and newly diagnosed type 2 diabetes, triggered by COVID-19 infection, increases the risk of severe opportunistic fungal infections and the associated mortality rates. |
format | Online Article Text |
id | pubmed-10058997 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-100589972023-03-30 Mucormycosis in a Patient with Severe COVID-19 Disease—The First Case Report in Romania and a Literature Review Mahler, Beatrice Parliteanu, Oana Andreea Alexe, Octavian Rîșcă Popazu, Corina Ene, Catalina Elena Timar, Bogdan Constantinescu, Tudor Medicina (Kaunas) Case Report Introduction: COVID-19 infection is often associated with a vast spectrum of opportunistic bacterial and fungal infections. Herein, we share a summary of the first case of COVID-19-associated mucormycosis (CAM) in a patient from Romania. Case presentation: A 51-year-old male non-smoker, with no known relevant medical history, who denied any previous alcohol use and was vaccinated against COVID-19 (complete scheme with Vaxzevria), was admitted to the hospital for severe COVID-19 infection. The first mucormycosis-related symptoms were reported on the eighth day of admission and were followed by the rapid deterioration of the patient’s condition and, consequently, death. The main aggravating factors, which were identified to be associated with the development of mucormycosis and with the poor outcome, were the association of severe COVID-19, new-onset COVID-19-triggered type 2 diabetes, and corticoid treatment for severe COVID-19. Conclusion: The association between severe COVID-19 and newly diagnosed type 2 diabetes, triggered by COVID-19 infection, increases the risk of severe opportunistic fungal infections and the associated mortality rates. MDPI 2023-03-11 /pmc/articles/PMC10058997/ /pubmed/36984555 http://dx.doi.org/10.3390/medicina59030555 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Mahler, Beatrice Parliteanu, Oana Andreea Alexe, Octavian Rîșcă Popazu, Corina Ene, Catalina Elena Timar, Bogdan Constantinescu, Tudor Mucormycosis in a Patient with Severe COVID-19 Disease—The First Case Report in Romania and a Literature Review |
title | Mucormycosis in a Patient with Severe COVID-19 Disease—The First Case Report in Romania and a Literature Review |
title_full | Mucormycosis in a Patient with Severe COVID-19 Disease—The First Case Report in Romania and a Literature Review |
title_fullStr | Mucormycosis in a Patient with Severe COVID-19 Disease—The First Case Report in Romania and a Literature Review |
title_full_unstemmed | Mucormycosis in a Patient with Severe COVID-19 Disease—The First Case Report in Romania and a Literature Review |
title_short | Mucormycosis in a Patient with Severe COVID-19 Disease—The First Case Report in Romania and a Literature Review |
title_sort | mucormycosis in a patient with severe covid-19 disease—the first case report in romania and a literature review |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10058997/ https://www.ncbi.nlm.nih.gov/pubmed/36984555 http://dx.doi.org/10.3390/medicina59030555 |
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