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Insights into In Vitro Adaptation of EV71 and Analysis of Reduced Virulence by In Silico Predictions
EV-A71 is a common viral pathogen that causes hand, foot and mouth disease. It is a single-stranded RNA virus that has a low fidelity RNA polymerase and, as a result, spontaneous mutations frequently occur in the EV-A71 genome. The mutations within the genome give rise to quasispecies within the vir...
Autores principales: | Koh, Jia Xuen, Masomian, Malihe, Anasir, Mohd Ishtiaq, Ong, Seng-Kai, Poh, Chit Laa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10059274/ https://www.ncbi.nlm.nih.gov/pubmed/36992213 http://dx.doi.org/10.3390/vaccines11030629 |
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