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Tetrodotoxin Decreases the Contractility of Mesenteric Arteries, Revealing the Contribution of Voltage-Gated Na(+) Channels in Vascular Tone Regulation

Tetrodotoxin (TTX) poisoning through the consumption of contaminated fish leads to lethal symptoms, including severe hypotension. This TTX-induced hypotension is likely due to the downfall of peripheral arterial resistance through direct or indirect effects on adrenergic signaling. TTX is a high-aff...

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Detalles Bibliográficos
Autores principales: Park, Joohee, Proux, Coralyne, Ehanno, William, Réthoré, Léa, Vessières, Emilie, Bourreau, Jennifer, Favre, Julie, Kauffenstein, Gilles, Mattei, César, Tricoire-Leignel, Hélène, Henrion, Daniel, Legendre, Claire, Legros, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10059581/
https://www.ncbi.nlm.nih.gov/pubmed/36976245
http://dx.doi.org/10.3390/md21030196