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Influence of Structural Parameters on the Performance of an Asymmetric Rhombus Micromixer with Baffles

As an important part of lab-on-a-chip and micro-total analysis systems, micromixers have a wide range of applications in biochemical analysis, pharmaceutical preparation and material synthesis. In the work, a novel rhombic separation and recombination micromixer with baffles was presented to further...

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Autores principales: Nai, Jiacheng, Zhang, Feng, Dong, Peng, Fu, Ting, Ge, Anle, Xu, Shuang, Pan, Yanqiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10059678/
https://www.ncbi.nlm.nih.gov/pubmed/36984952
http://dx.doi.org/10.3390/mi14030545
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author Nai, Jiacheng
Zhang, Feng
Dong, Peng
Fu, Ting
Ge, Anle
Xu, Shuang
Pan, Yanqiao
author_facet Nai, Jiacheng
Zhang, Feng
Dong, Peng
Fu, Ting
Ge, Anle
Xu, Shuang
Pan, Yanqiao
author_sort Nai, Jiacheng
collection PubMed
description As an important part of lab-on-a-chip and micro-total analysis systems, micromixers have a wide range of applications in biochemical analysis, pharmaceutical preparation and material synthesis. In the work, a novel rhombic separation and recombination micromixer with baffles was presented to further improve the performance of the micromixer and study the effect of multiple structural parameters on mixing. The effects of the rhombic angle, the width ratio of sub-channel and the size and relative positions of baffles on the mixing index were studied numerically at different Reynolds numbers (Re), and the sensitivity of the mixing index to various structures was also investigated. The results showed that the mixing index increased with the subchannel’s width ratio and slowly decreased after reaching the peak value in the range of Re from 0.1 to 60. The maximum mixing index appeared when the width ratio was 6.5. The pressure drops in the microchannel were proportional to the width ratio. The mixing effect can be further improved by adding baffle structure to asymmetric rhombus micromixer, and more baffle quantity and larger baffle height were beneficial to the improvement of the mixing index. The research results can provide reference and new ideas for the structure design of passive micromixers.
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spelling pubmed-100596782023-03-30 Influence of Structural Parameters on the Performance of an Asymmetric Rhombus Micromixer with Baffles Nai, Jiacheng Zhang, Feng Dong, Peng Fu, Ting Ge, Anle Xu, Shuang Pan, Yanqiao Micromachines (Basel) Article As an important part of lab-on-a-chip and micro-total analysis systems, micromixers have a wide range of applications in biochemical analysis, pharmaceutical preparation and material synthesis. In the work, a novel rhombic separation and recombination micromixer with baffles was presented to further improve the performance of the micromixer and study the effect of multiple structural parameters on mixing. The effects of the rhombic angle, the width ratio of sub-channel and the size and relative positions of baffles on the mixing index were studied numerically at different Reynolds numbers (Re), and the sensitivity of the mixing index to various structures was also investigated. The results showed that the mixing index increased with the subchannel’s width ratio and slowly decreased after reaching the peak value in the range of Re from 0.1 to 60. The maximum mixing index appeared when the width ratio was 6.5. The pressure drops in the microchannel were proportional to the width ratio. The mixing effect can be further improved by adding baffle structure to asymmetric rhombus micromixer, and more baffle quantity and larger baffle height were beneficial to the improvement of the mixing index. The research results can provide reference and new ideas for the structure design of passive micromixers. MDPI 2023-02-26 /pmc/articles/PMC10059678/ /pubmed/36984952 http://dx.doi.org/10.3390/mi14030545 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Nai, Jiacheng
Zhang, Feng
Dong, Peng
Fu, Ting
Ge, Anle
Xu, Shuang
Pan, Yanqiao
Influence of Structural Parameters on the Performance of an Asymmetric Rhombus Micromixer with Baffles
title Influence of Structural Parameters on the Performance of an Asymmetric Rhombus Micromixer with Baffles
title_full Influence of Structural Parameters on the Performance of an Asymmetric Rhombus Micromixer with Baffles
title_fullStr Influence of Structural Parameters on the Performance of an Asymmetric Rhombus Micromixer with Baffles
title_full_unstemmed Influence of Structural Parameters on the Performance of an Asymmetric Rhombus Micromixer with Baffles
title_short Influence of Structural Parameters on the Performance of an Asymmetric Rhombus Micromixer with Baffles
title_sort influence of structural parameters on the performance of an asymmetric rhombus micromixer with baffles
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10059678/
https://www.ncbi.nlm.nih.gov/pubmed/36984952
http://dx.doi.org/10.3390/mi14030545
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