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Co-Delivery of the Human NY-ESO-1 Tumor-Associated Antigen and Alpha-GalactosylCeramide by Filamentous Bacteriophages Strongly Enhances the Expansion of Tumor-Specific CD8+ T Cells

Tumor-associated antigens (TAAs) represent attractive targets in the development of anti-cancer vaccines. The filamentous bacteriophage is a safe and versatile delivery nanosystem, and recombinant bacteriophages expressing TAA-derived peptides at a high density on the viral coat proteins improve TAA...

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Detalles Bibliográficos
Autores principales: Manco, Roberta, D’Apice, Luciana, Trovato, Maria, Lione, Lucia, Salvatori, Erika, Pinto, Eleonora, Compagnone, Mirco, Aurisicchio, Luigi, De Berardinis, Piergiuseppe, Sartorius, Rossella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10059692/
https://www.ncbi.nlm.nih.gov/pubmed/36992381
http://dx.doi.org/10.3390/v15030672