Cargando…

Recent Advances in the Lipid Nanoparticle-Mediated Delivery of mRNA Vaccines

Lipid nanoparticles (LNPs) have recently emerged as one of the most advanced technologies for the highly efficient in vivo delivery of exogenous mRNA, particularly for COVID-19 vaccine delivery. LNPs comprise four different lipids: ionizable lipids, helper or neutral lipids, cholesterol, and lipids...

Descripción completa

Detalles Bibliográficos
Autores principales:	Swetha, K., Kotla, Niranjan G., Tunki, Lakshmi, Jayaraj, Arya, Bhargava, Suresh K., Hu, Haitao, Bonam, Srinivasa Reddy, Kurapati, Rajendra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10059764/ https://www.ncbi.nlm.nih.gov/pubmed/36992242 http://dx.doi.org/10.3390/vaccines11030658

Ejemplares similares

Optimization of solid lipid nanoparticles prepared by a single emulsification-solvent evaporation method
por: Pooja, Deep, et al.
Publicado: (2015)

Potential immuno-nanomedicine strategies to fight COVID-19 like pulmonary infections
por: Bonam, Srinivasa Reddy, et al.
Publicado: (2021)

Recent Advances in Lipid Nanoparticles for Delivery of mRNA
por: Yang, Lei, et al.
Publicado: (2022)

Recent Advances in Site-Specific Lipid Nanoparticles for mRNA Delivery
por: Xu, Xiao, et al.
Publicado: (2023)

THEME: “Vaccines and Vaccine Adjuvants/Immunomodulators for Infectious Diseases”
por: Retnakumar, Sruthi Vijaya, et al.
Publicado: (2023)

Lipid nanoparticles for mRNA delivery
por: Hou, Xucheng, et al.
Publicado: (2021)

Delivery of mRNA to platelets using lipid nanoparticles
por: Novakowski, S., et al.
Publicado: (2019)

Role of the PD-1 and PD-L1 axis in COVID-19
por: R Bonam, Srinivasa, et al.
Publicado: (2022)

An Orally Administrated Hyaluronan Functionalized Polymeric Hybrid Nanoparticle System for Colon-Specific Drug Delivery
por: Kotla, Niranjan G., et al.
Publicado: (2019)

Ionizable lipid nanoparticles for in utero mRNA delivery
por: Riley, Rachel S., et al.
Publicado: (2021)

Recent advances in lipid nanoparticles for delivery of nucleic acid, mRNA, and gene editing-based therapeutics
por: Mukai, Hidefumi, et al.
Publicado: (2022)

HSPA8/HSC70 in Immune Disorders: A Molecular Rheostat that Adjusts Chaperone-Mediated Autophagy Substrates
por: Bonam, Srinivasa Reddy, et al.
Publicado: (2019)

Lysosomes as a therapeutic target
por: Bonam, Srinivasa Reddy, et al.
Publicado: (2019)

Autophagy-Lysosomal Pathway as Potential Therapeutic Target in Parkinson’s Disease
por: Bonam, Srinivasa Reddy, et al.
Publicado: (2021)

No detectable association of IGF2BP2 and SLC30A8 genes with type 2 diabetes in the population of Hyderabad, India()
por: Kommoju, Uma Jyothi, et al.
Publicado: (2013)

Lipid Nanoparticle Delivery Systems to Enable mRNA-Based Therapeutics
por: Semple, Sean C., et al.
Publicado: (2022)

Association of TCF7L2 Gene Polymorphisms with T2DM in the Population of Hyderabad, India
por: Uma Jyothi, Kommoju, et al.
Publicado: (2013)

Association of CDKAL1, CDKN2A/B & HHEX gene polymorphisms with type 2 diabetes mellitus in the population of Hyderabad, India
por: Kommoju, Uma Jyothi, et al.
Publicado: (2016)

Epigenetic Lens to Visualize the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) Infection in COVID-19 Pandemic
por: Saksena, Nitin, et al.
Publicado: (2021)

Retrospective analysis on the immunopotentiating mechanism of an emulsion-based vaccine adjuvant on human antigen presenting cells
por: Bonam, Srinivasa Reddy, et al.
Publicado: (2023)

Editorial: Innate immune responses to SARS-CoV-2 in infected and vaccinated individuals
por: Saksena, Nitin K., et al.
Publicado: (2023)

Lipid carriers for mRNA delivery
por: Zhang, Wanting, et al.
Publicado: (2023)

Lipid Nanoparticles for Organ-Specific mRNA Therapeutic Delivery
por: Żak, Magdalena M., et al.
Publicado: (2021)

Lipid Nanoparticles for mRNA Delivery to Enhance Cancer Immunotherapy
por: Wang, Hong-Li, et al.
Publicado: (2022)

Lipid Nanoparticles as Carriers for Bioactive Delivery
por: Dhiman, Neerupma, et al.
Publicado: (2021)

PHYTOCHEMICAL, PHARMACOLOGICAL AND BIOLOGICAL PROFILES OF TRAGIA SPECIES (FAMILY: EUPHORBIACEAE)
por: Reddy, Bonam Srinivasa, et al.
Publicado: (2017)

Progress and Challenges in the Use of MAP1LC3 as a Legitimate Marker for Measuring Dynamic Autophagy In Vivo
por: Bonam, Srinivasa Reddy, et al.
Publicado: (2020)

IFN-γ Induces PD-L1 Expression in Primed Human Basophils
por: Bonam, Srinivasa Reddy, et al.
Publicado: (2022)

Understanding Intracellular Biology to Improve mRNA Delivery by Lipid Nanoparticles
por: Hunter, Morag Rose, et al.
Publicado: (2023)

Long-term storage of lipid-like nanoparticles for mRNA delivery
por: Zhao, Pengxuan, et al.
Publicado: (2020)

In utero delivery of mRNA to the heart, diaphragm and muscle with lipid nanoparticles
por: Gao, Kewa, et al.
Publicado: (2023)

Lipid nanoparticle-based mRNA delivery systems for cancer immunotherapy
por: Han, Jieun, et al.
Publicado: (2023)

Optimization of Lipid Nanoformulations for Effective mRNA Delivery
por: Chen, Huiling, et al.
Publicado: (2022)

Recent Advances in Lipid-Based Drug Delivery
por: Nishida, Koyo
Publicado: (2021)

Functionalized lipid-like nanoparticles for in vivo mRNA delivery and base editing
por: Zhang, Xinfu, et al.
Publicado: (2020)

Aerosolizable Lipid Nanoparticles for Pulmonary Delivery of mRNA through Design of Experiments
por: Zhang, Hairui, et al.
Publicado: (2020)

Biodrug Delivery Systems: Do mRNA Lipid Nanoparticles Come of Age?
por: Puccetti, Matteo, et al.
Publicado: (2023)

Recent advances in siRNA delivery mediated by lipid-based nanoparticles
por: Yonezawa, Sei, et al.
Publicado: (2020)

A Recent Update: Solid Lipid Nanoparticles for Effective Drug Delivery
por: Pandey, Sonia, et al.
Publicado: (2022)

Adjunct Immunotherapies for the Management of Severely Ill COVID-19 Patients
por: Bonam, Srinivasa Reddy, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_rddnq0q2bgj8jvn15r0lrt694i