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Corneal Neurotization—Indications, Surgical Techniques and Outcomes
Corneal neurotization is a promising surgical approach for the treatment of moderate to severe neurotrophic keratopathy. This technique aims to restore corneal sensation by transferring healthy nerves, either directly or via a conduit, to the anesthetic cornea. This review provides a report on the c...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10059768/ https://www.ncbi.nlm.nih.gov/pubmed/36983215 http://dx.doi.org/10.3390/jcm12062214 |
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author | Dragnea, Diana Carmen Krolo, Iva Koppen, Carina Faris, Callum Van den Bogerd, Bert Ní Dhubhghaill, Sorcha |
author_facet | Dragnea, Diana Carmen Krolo, Iva Koppen, Carina Faris, Callum Van den Bogerd, Bert Ní Dhubhghaill, Sorcha |
author_sort | Dragnea, Diana Carmen |
collection | PubMed |
description | Corneal neurotization is a promising surgical approach for the treatment of moderate to severe neurotrophic keratopathy. This technique aims to restore corneal sensation by transferring healthy nerves, either directly or via a conduit, to the anesthetic cornea. This review provides a report on the current state of development, evidence, and experience in the field. We summarize the data available from clinical reports and case series, placing an emphasis on the diversity of the surgical techniques reported. While these data are encouraging, they also highlight the need for a consensus in reporting outcomes and highlight how the next step will involve validating putative outcome parameters when researching and reporting corneal neurotization surgery. |
format | Online Article Text |
id | pubmed-10059768 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-100597682023-03-30 Corneal Neurotization—Indications, Surgical Techniques and Outcomes Dragnea, Diana Carmen Krolo, Iva Koppen, Carina Faris, Callum Van den Bogerd, Bert Ní Dhubhghaill, Sorcha J Clin Med Review Corneal neurotization is a promising surgical approach for the treatment of moderate to severe neurotrophic keratopathy. This technique aims to restore corneal sensation by transferring healthy nerves, either directly or via a conduit, to the anesthetic cornea. This review provides a report on the current state of development, evidence, and experience in the field. We summarize the data available from clinical reports and case series, placing an emphasis on the diversity of the surgical techniques reported. While these data are encouraging, they also highlight the need for a consensus in reporting outcomes and highlight how the next step will involve validating putative outcome parameters when researching and reporting corneal neurotization surgery. MDPI 2023-03-13 /pmc/articles/PMC10059768/ /pubmed/36983215 http://dx.doi.org/10.3390/jcm12062214 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Dragnea, Diana Carmen Krolo, Iva Koppen, Carina Faris, Callum Van den Bogerd, Bert Ní Dhubhghaill, Sorcha Corneal Neurotization—Indications, Surgical Techniques and Outcomes |
title | Corneal Neurotization—Indications, Surgical Techniques and Outcomes |
title_full | Corneal Neurotization—Indications, Surgical Techniques and Outcomes |
title_fullStr | Corneal Neurotization—Indications, Surgical Techniques and Outcomes |
title_full_unstemmed | Corneal Neurotization—Indications, Surgical Techniques and Outcomes |
title_short | Corneal Neurotization—Indications, Surgical Techniques and Outcomes |
title_sort | corneal neurotization—indications, surgical techniques and outcomes |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10059768/ https://www.ncbi.nlm.nih.gov/pubmed/36983215 http://dx.doi.org/10.3390/jcm12062214 |
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