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Corneal Neurotization—Indications, Surgical Techniques and Outcomes

Corneal neurotization is a promising surgical approach for the treatment of moderate to severe neurotrophic keratopathy. This technique aims to restore corneal sensation by transferring healthy nerves, either directly or via a conduit, to the anesthetic cornea. This review provides a report on the c...

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Autores principales: Dragnea, Diana Carmen, Krolo, Iva, Koppen, Carina, Faris, Callum, Van den Bogerd, Bert, Ní Dhubhghaill, Sorcha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10059768/
https://www.ncbi.nlm.nih.gov/pubmed/36983215
http://dx.doi.org/10.3390/jcm12062214
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author Dragnea, Diana Carmen
Krolo, Iva
Koppen, Carina
Faris, Callum
Van den Bogerd, Bert
Ní Dhubhghaill, Sorcha
author_facet Dragnea, Diana Carmen
Krolo, Iva
Koppen, Carina
Faris, Callum
Van den Bogerd, Bert
Ní Dhubhghaill, Sorcha
author_sort Dragnea, Diana Carmen
collection PubMed
description Corneal neurotization is a promising surgical approach for the treatment of moderate to severe neurotrophic keratopathy. This technique aims to restore corneal sensation by transferring healthy nerves, either directly or via a conduit, to the anesthetic cornea. This review provides a report on the current state of development, evidence, and experience in the field. We summarize the data available from clinical reports and case series, placing an emphasis on the diversity of the surgical techniques reported. While these data are encouraging, they also highlight the need for a consensus in reporting outcomes and highlight how the next step will involve validating putative outcome parameters when researching and reporting corneal neurotization surgery.
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spelling pubmed-100597682023-03-30 Corneal Neurotization—Indications, Surgical Techniques and Outcomes Dragnea, Diana Carmen Krolo, Iva Koppen, Carina Faris, Callum Van den Bogerd, Bert Ní Dhubhghaill, Sorcha J Clin Med Review Corneal neurotization is a promising surgical approach for the treatment of moderate to severe neurotrophic keratopathy. This technique aims to restore corneal sensation by transferring healthy nerves, either directly or via a conduit, to the anesthetic cornea. This review provides a report on the current state of development, evidence, and experience in the field. We summarize the data available from clinical reports and case series, placing an emphasis on the diversity of the surgical techniques reported. While these data are encouraging, they also highlight the need for a consensus in reporting outcomes and highlight how the next step will involve validating putative outcome parameters when researching and reporting corneal neurotization surgery. MDPI 2023-03-13 /pmc/articles/PMC10059768/ /pubmed/36983215 http://dx.doi.org/10.3390/jcm12062214 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Dragnea, Diana Carmen
Krolo, Iva
Koppen, Carina
Faris, Callum
Van den Bogerd, Bert
Ní Dhubhghaill, Sorcha
Corneal Neurotization—Indications, Surgical Techniques and Outcomes
title Corneal Neurotization—Indications, Surgical Techniques and Outcomes
title_full Corneal Neurotization—Indications, Surgical Techniques and Outcomes
title_fullStr Corneal Neurotization—Indications, Surgical Techniques and Outcomes
title_full_unstemmed Corneal Neurotization—Indications, Surgical Techniques and Outcomes
title_short Corneal Neurotization—Indications, Surgical Techniques and Outcomes
title_sort corneal neurotization—indications, surgical techniques and outcomes
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10059768/
https://www.ncbi.nlm.nih.gov/pubmed/36983215
http://dx.doi.org/10.3390/jcm12062214
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