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Bladder Neck Obstruction: Experience and Management in a Sperm Bank

Primary Bladder Neck Obstruction (PBNO) management provides medical and surgical treatment, such as transurethral incisions that can lead to retrograde ejaculation. The aim of this study was to investigate the maintenance of anterograde ejaculation and semen quality before and after this surgical pr...

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Autores principales: Hirsch, Maria Neve, Pallotti, Francesco, Faja, Fabiana, Buonacquisto, Alessandra, Cicolani, Gaia, Conflitti, Anna Chiara, Di Chiano, Silvia, Lenzi, Andrea, Lombardo, Francesco, Paoli, Donatella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10059771/
https://www.ncbi.nlm.nih.gov/pubmed/36983997
http://dx.doi.org/10.3390/life13030842
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author Hirsch, Maria Neve
Pallotti, Francesco
Faja, Fabiana
Buonacquisto, Alessandra
Cicolani, Gaia
Conflitti, Anna Chiara
Di Chiano, Silvia
Lenzi, Andrea
Lombardo, Francesco
Paoli, Donatella
author_facet Hirsch, Maria Neve
Pallotti, Francesco
Faja, Fabiana
Buonacquisto, Alessandra
Cicolani, Gaia
Conflitti, Anna Chiara
Di Chiano, Silvia
Lenzi, Andrea
Lombardo, Francesco
Paoli, Donatella
author_sort Hirsch, Maria Neve
collection PubMed
description Primary Bladder Neck Obstruction (PBNO) management provides medical and surgical treatment, such as transurethral incisions that can lead to retrograde ejaculation. The aim of this study was to investigate the maintenance of anterograde ejaculation and semen quality before and after this surgical procedure. A retrospective evaluation was carried out between 2011 and 2020. A total of 73 patients diagnosed with PBNO were recruited. Ejaculatory function, semen quality, and the fertility of recruited subjects were evaluated. Semen parameters—Baseline, 8.2% of patients were oligozoospermic and 12.3% had a semen volume below the WHO 2010 fifth percentile. Post-surgery, 20% of patients were oligozoospermic. We detected a significant decrease in total sperm number, a significant increase in the number of abnormal forms, and a reduction in the leukocyte concentration. Ejaculatory function—A total of 7.7% of patients reported anejaculation after transurethral incision of the bladder neck. Fertility—9.2% of the patients already had children before surgery; 13.8% had naturally conceived children in the years following surgery; 76.9% had no desire for paternity at the time. Our data have important implications for sperm bank management. The alterations in semen parameters and the risk of anejaculation suggest that the use of sperm cryopreservation before surgery for PBNO should be encouraged.
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spelling pubmed-100597712023-03-30 Bladder Neck Obstruction: Experience and Management in a Sperm Bank Hirsch, Maria Neve Pallotti, Francesco Faja, Fabiana Buonacquisto, Alessandra Cicolani, Gaia Conflitti, Anna Chiara Di Chiano, Silvia Lenzi, Andrea Lombardo, Francesco Paoli, Donatella Life (Basel) Communication Primary Bladder Neck Obstruction (PBNO) management provides medical and surgical treatment, such as transurethral incisions that can lead to retrograde ejaculation. The aim of this study was to investigate the maintenance of anterograde ejaculation and semen quality before and after this surgical procedure. A retrospective evaluation was carried out between 2011 and 2020. A total of 73 patients diagnosed with PBNO were recruited. Ejaculatory function, semen quality, and the fertility of recruited subjects were evaluated. Semen parameters—Baseline, 8.2% of patients were oligozoospermic and 12.3% had a semen volume below the WHO 2010 fifth percentile. Post-surgery, 20% of patients were oligozoospermic. We detected a significant decrease in total sperm number, a significant increase in the number of abnormal forms, and a reduction in the leukocyte concentration. Ejaculatory function—A total of 7.7% of patients reported anejaculation after transurethral incision of the bladder neck. Fertility—9.2% of the patients already had children before surgery; 13.8% had naturally conceived children in the years following surgery; 76.9% had no desire for paternity at the time. Our data have important implications for sperm bank management. The alterations in semen parameters and the risk of anejaculation suggest that the use of sperm cryopreservation before surgery for PBNO should be encouraged. MDPI 2023-03-20 /pmc/articles/PMC10059771/ /pubmed/36983997 http://dx.doi.org/10.3390/life13030842 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Hirsch, Maria Neve
Pallotti, Francesco
Faja, Fabiana
Buonacquisto, Alessandra
Cicolani, Gaia
Conflitti, Anna Chiara
Di Chiano, Silvia
Lenzi, Andrea
Lombardo, Francesco
Paoli, Donatella
Bladder Neck Obstruction: Experience and Management in a Sperm Bank
title Bladder Neck Obstruction: Experience and Management in a Sperm Bank
title_full Bladder Neck Obstruction: Experience and Management in a Sperm Bank
title_fullStr Bladder Neck Obstruction: Experience and Management in a Sperm Bank
title_full_unstemmed Bladder Neck Obstruction: Experience and Management in a Sperm Bank
title_short Bladder Neck Obstruction: Experience and Management in a Sperm Bank
title_sort bladder neck obstruction: experience and management in a sperm bank
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10059771/
https://www.ncbi.nlm.nih.gov/pubmed/36983997
http://dx.doi.org/10.3390/life13030842
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