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Potential Roles of Melatonin in Doxorubicin-Induced Cardiotoxicity: From Cellular Mechanisms to Clinical Application

Doxorubicin is a potent chemotherapeutic drug; however, its clinical application has been limited due to its cardiotoxicity. One of the major mechanisms of doxorubicin-induced cardiotoxicity is the induction of oxidative stress. Evidence from in vitro and in vivo studies demonstrates that melatonin...

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Detalles Bibliográficos
Autores principales: Attachaipanich, Tanawat, Chattipakorn, Siriporn C., Chattipakorn, Nipon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10059789/
https://www.ncbi.nlm.nih.gov/pubmed/36986646
http://dx.doi.org/10.3390/pharmaceutics15030785