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Antibacterial Enhancement of High-Efficiency Particulate Air Filters Modified with Graphene-Silver Hybrid Material

Bacterial infections are a major concern as antibiotic resistance poses a great threat, therefore leading to a race against time into finding new drugs or improving the existing resources. Nanomaterials with high surface area and bactericidal properties are the most promising ones that help combatin...

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Autores principales: Ciorîță, Alexandra, Suciu, Maria, Coroş, Maria, Varodi, Codruța, Pogăcean, Florina, Măgeruşan, Lidia, Mirel, Valentin, Ștefan-van Staden, Raluca-Ioana, Pruneanu, Stela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10059912/
https://www.ncbi.nlm.nih.gov/pubmed/36985318
http://dx.doi.org/10.3390/microorganisms11030745
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author Ciorîță, Alexandra
Suciu, Maria
Coroş, Maria
Varodi, Codruța
Pogăcean, Florina
Măgeruşan, Lidia
Mirel, Valentin
Ștefan-van Staden, Raluca-Ioana
Pruneanu, Stela
author_facet Ciorîță, Alexandra
Suciu, Maria
Coroş, Maria
Varodi, Codruța
Pogăcean, Florina
Măgeruşan, Lidia
Mirel, Valentin
Ștefan-van Staden, Raluca-Ioana
Pruneanu, Stela
author_sort Ciorîță, Alexandra
collection PubMed
description Bacterial infections are a major concern as antibiotic resistance poses a great threat, therefore leading to a race against time into finding new drugs or improving the existing resources. Nanomaterials with high surface area and bactericidal properties are the most promising ones that help combating microbial infections. In our case, graphene decorated with silver nanoparticles Gr-Ag (5 wt% Ag) exhibited inhibitory capacity against S. aureus and E. coli. The newly formed hybrid material was next incubated with high-efficiency particulate air (HEPA) filter, to obtain one with bactericidal properties. The modified filter had greater inhibitory action against the tested strains, compared to the control, and the effect was better against the Gram-negative model. Even if the bacteria remained attached to the filters, their colony forming unit capacity was affected by the Gr-Ag (5 wt% Ag) hybrid material, when they were subsequently re-cultured on fresh agar media. Therefore, the HEPA filter modified with Gr-Ag (5 wt% Ag) has high antibacterial properties that may substantially improve the existing technology.
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spelling pubmed-100599122023-03-30 Antibacterial Enhancement of High-Efficiency Particulate Air Filters Modified with Graphene-Silver Hybrid Material Ciorîță, Alexandra Suciu, Maria Coroş, Maria Varodi, Codruța Pogăcean, Florina Măgeruşan, Lidia Mirel, Valentin Ștefan-van Staden, Raluca-Ioana Pruneanu, Stela Microorganisms Article Bacterial infections are a major concern as antibiotic resistance poses a great threat, therefore leading to a race against time into finding new drugs or improving the existing resources. Nanomaterials with high surface area and bactericidal properties are the most promising ones that help combating microbial infections. In our case, graphene decorated with silver nanoparticles Gr-Ag (5 wt% Ag) exhibited inhibitory capacity against S. aureus and E. coli. The newly formed hybrid material was next incubated with high-efficiency particulate air (HEPA) filter, to obtain one with bactericidal properties. The modified filter had greater inhibitory action against the tested strains, compared to the control, and the effect was better against the Gram-negative model. Even if the bacteria remained attached to the filters, their colony forming unit capacity was affected by the Gr-Ag (5 wt% Ag) hybrid material, when they were subsequently re-cultured on fresh agar media. Therefore, the HEPA filter modified with Gr-Ag (5 wt% Ag) has high antibacterial properties that may substantially improve the existing technology. MDPI 2023-03-14 /pmc/articles/PMC10059912/ /pubmed/36985318 http://dx.doi.org/10.3390/microorganisms11030745 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ciorîță, Alexandra
Suciu, Maria
Coroş, Maria
Varodi, Codruța
Pogăcean, Florina
Măgeruşan, Lidia
Mirel, Valentin
Ștefan-van Staden, Raluca-Ioana
Pruneanu, Stela
Antibacterial Enhancement of High-Efficiency Particulate Air Filters Modified with Graphene-Silver Hybrid Material
title Antibacterial Enhancement of High-Efficiency Particulate Air Filters Modified with Graphene-Silver Hybrid Material
title_full Antibacterial Enhancement of High-Efficiency Particulate Air Filters Modified with Graphene-Silver Hybrid Material
title_fullStr Antibacterial Enhancement of High-Efficiency Particulate Air Filters Modified with Graphene-Silver Hybrid Material
title_full_unstemmed Antibacterial Enhancement of High-Efficiency Particulate Air Filters Modified with Graphene-Silver Hybrid Material
title_short Antibacterial Enhancement of High-Efficiency Particulate Air Filters Modified with Graphene-Silver Hybrid Material
title_sort antibacterial enhancement of high-efficiency particulate air filters modified with graphene-silver hybrid material
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10059912/
https://www.ncbi.nlm.nih.gov/pubmed/36985318
http://dx.doi.org/10.3390/microorganisms11030745
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