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Astragalus Saponins, Astragaloside VII and Newly Synthesized Derivatives, Induce Dendritic Cell Maturation and T Cell Activation

Astragaloside VII (AST VII), a triterpenic saponin isolated from Astragalus species, shows promise as a vaccine adjuvant, as it supported a balanced Th1/Th2 immune response in previous in vivo studies. However, the underlying mechanisms of its adjuvant activity have not been defined. Here, we invest...

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Detalles Bibliográficos
Autores principales: Yakubogullari, Nilgun, Cagir, Ali, Bedir, Erdal, Sag, Duygu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10059926/
https://www.ncbi.nlm.nih.gov/pubmed/36992079
http://dx.doi.org/10.3390/vaccines11030495