Fast and sensitive GCaMP calcium indicators for imaging neural populations

Calcium imaging with protein-based indicators(1,2) is widely used to follow neural activity in intact nervous systems, but current protein sensors report neural activity at timescales much slower than electrical signalling and are limited by trade-offs between sensitivity and kinetics. Here we used...

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Detalles Bibliográficos
Autores principales: Zhang, Yan, Rózsa, Márton, Liang, Yajie, Bushey, Daniel, Wei, Ziqiang, Zheng, Jihong, Reep, Daniel, Broussard, Gerard Joey, Tsang, Arthur, Tsegaye, Getahun, Narayan, Sujatha, Obara, Christopher J., Lim, Jing-Xuan, Patel, Ronak, Zhang, Rongwei, Ahrens, Misha B., Turner, Glenn C., Wang, Samuel S.-H., Korff, Wyatt L., Schreiter, Eric R., Svoboda, Karel, Hasseman, Jeremy P., Kolb, Ilya, Looger, Loren L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060165/
https://www.ncbi.nlm.nih.gov/pubmed/36922596
http://dx.doi.org/10.1038/s41586-023-05828-9

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